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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

542 questions in 42 reviews · Skin

current versions
No studies 542 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Chemical peeling vs combined chemical peeling plus any active intervention
Quality of life · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Chemical peeling vs needling
Participant‐reported scar improvement (long‐term) · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Chemical peeling vs needling
Quality of life · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Injectable fillers vs placebo or no treatment
Participant‐assessed scar improvement (long‐term) · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Injectable fillers vs placebo or no treatment
Quality of life · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Fractional laser vs non‐fractional non‐ablative laser
Participant satisfaction · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Fractional laser vs non‐fractional non‐ablative laser
Quality of life · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Fractional laser vs radiofrequency
Participant‐reported scar improvement (long‐term) · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Fractional laser vs radiofrequency
Investigator‐assessed adverse events (short‐term) · people with acne scars
Interventions for acne scars (2016) · Cochrane
no estimate extractedNRNo studies
Metronidazole vs placebo
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Clinician's Erythema Assessment ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel
Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Minocycline 45 mg vs minocycline 45 mg + azelaic acid gel
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical metronidazole vs oral (oxy)tetracycline
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical metronidazole vs oral (oxy)tetracycline
Time needed until improvement ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical metronidazole vs oral (oxy)tetracycline
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Low dose isotretinoin 0.3 mg/kg vs doxycycline 50‐100 mg
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Low dose isotretinoin 0.3 mg/kg vs doxycycline 50‐100 mg
Time needed until improvement ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Low dose isotretinoin 0.3 mg/kg vs doxycycline 50‐100 mg
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs Nd:YAG laser
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs Nd:YAG laser
Physician‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs Nd:YAG laser
Lesion count ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs Nd:YAG laser
Time until improvement ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs Nd:YAG laser
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs intense pulsed light therapy
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs intense pulsed light therapy
Physician‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs intense pulsed light therapy
Lesion count ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs intense pulsed light therapy
Time until improvement ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Pulsed dye laser vs intense pulsed light therapy
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Azelaic acid vs placebo
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical ivermectin vs placebo
Assessment of erythema or telangiectasia ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical ivermectin vs placebo
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical brimonidine vs vehicle
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical brimonidine vs vehicle
Physician‐assessed improvement in rosacea severity ‐ not reported · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical brimonidine vs vehicle
Lesion count ‐ not reported · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical brimonidine vs vehicle
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical azelaic acid vs topical metronidazole
HRQOL ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical azelaic acid vs topical metronidazole
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical ivermectin vs topical metronidazole
Assessment of erythema or telangiectasia ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Topical ivermectin vs topical metronidazole
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Ciclosporin ophthalmic emulsion 0.05% vs artificial tears
Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with ocular rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Ciclosporin ophthalmic emulsion 0.05% vs artificial tears
Assessment of erythema or telangiectasia ‐ not measured · Participants with ocular rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Ciclosporin ophthalmic emulsion 0.05% vs artificial tears
Lesion count ‐ not measured · Participants with ocular rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Ciclosporin ophthalmic emulsion 0.05% vs artificial tears
Time needed until improvement of the skin lesions ‐ not measured · Participants with ocular rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Ciclosporin ophthalmic emulsion 0.05% vs artificial tears
Duration of remission ‐ not measured · Participants with ocular rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Clindamycin phosphate 1.2% + tretinoin 0.025% gel vs placebo
Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Clindamycin phosphate 1.2% + tretinoin 0.025% gel vs placebo
Time needed until improvement of the skin lesions ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies
Clindamycin phosphate 1.2% + tretinoin 0.025% gel vs placebo
Duration of remission ‐ not measured · Participants with rosacea
Interventions for rosacea (2015) · Cochrane
no estimate extractedNRNo studies