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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,344 questions in 217 reviews · Oral Health
current versionsNo studies 1,344 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Hypnosis vs Conventional treatment Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before or during LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Completion of dental treatment: included studies did not report on this outcome | NR | No studies |
Clindamycin + SRP vs Doxycycline + SRP Adverse events · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included study has not reported adverse events | NR | No studies |
Metronidazole + SRP vs SRP Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive) · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Audiovisual distraction vs Conventional treatment Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth Costs (days off work/study; direct costs of retention or removal) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth (2020) · Cochrane | Costs: Not measured. The included studies did not measure days off work/study or direct costs associated with retention or removal of wisdom teeth and treatment of associated symptoms or complications. | 0 studies | No studies |
Clindamycin + SRP vs Doxycycline + SRP Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional) Adverse effects · Adults with mandibular third molars requiring removal · up to 30 days Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth Health-related quality of life · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth Surgical removal versus retention for the management of asymptomatic disease‐free impacted wisdom teeth (2020) · Cochrane | Health-related quality of life: Our primary outcome was not assessed in the included studies. | 0 studies | No studies |
The wand (computer-controlled LA delivery system) vs Sleeper One (electronic LA delivery system) Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Successful LA/painless treatment: included studies did not report on this outcome | NR | No studies |
Lingual nerve retractor (subperiosteal or Free's) vs No retractor Adverse effects (reactionary bleeding) · Adults with mandibular third molars requiring removal · up to 30 days Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Lingual nerve retractor (subperiosteal or Free's) vs No retractor Alveolar osteitis · Adults with mandibular third molars requiring removal · 1 week Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional) Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal · >6 months Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Pre-cooling of the injection site vs Conventional treatment Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · Immediately before LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Successful LA/painless treatment: included studies did not report on this outcome | NR | No studies |
Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do) Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · In advance of LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
Camouflage syringe vs Conventional syringe Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Adverse effects: included studies did not report on this outcome | NR | No studies |
Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment, saline, or water Changes in microbiome in oral cavity, nasal cavity, oro- or nasopharynx · Patients with suspected or confirmed COVID-19 infection Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed… (2020) · Cochrane | No data available (no included studies) | 0 studies | No studies |
Clindamycin + SRP vs Doxycycline + SRP Percentage of closed pockets · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Video modelling acclimatisation for LA vs Oral hygiene video Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · In advance of LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Adverse effects: included studies did not report on this outcome | NR | No studies |
Video modelling acclimatisation for LA vs Oral hygiene video Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · In advance of LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Successful LA/painless treatment: included studies did not report on this outcome | NR | No studies |
Coronectomy vs Complete extraction (odontectomy) Alveolar osteitis · Adults with mandibular third molars requiring removal · 1 week Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Fibre-optic transillumination (FOTI, including white light scattering and near infrared) vs Reference standard: histology or enhanced visual-tactile examination Outcome NR · Adults presenting asymptomatically or suspected of having root caries (in vivo); extracted teeth of adults (in vitro) Tests to detect and inform the diagnosis of root caries (2020) · Cochrane | Fibre-optic transillumination was a pre-specified eligible index test but no diagnostic test accuracy study of fibre-optic transillumination was included. | 0 studies | No studies |
The wand (computer-controlled LA delivery system) vs Sleeper One (electronic LA delivery system) Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
Counter-stimulation and distraction (combined) vs Conventional treatment Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Completion of dental treatment: included studies did not report on this outcome | NR | No studies |
Lingual nerve retractor (subperiosteal or Free's) vs No retractor Postoperative pain · Adults with mandibular third molars requiring removal · 24 hours Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Counter-stimulation and distraction (combined) vs Conventional treatment Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
Video modelling acclimatisation for LA vs Oral hygiene video Patient satisfaction: measured by questionnaires · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · In advance of LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Patient satisfaction: included studies did not report on this outcome | NR | No studies |
No recall interval / patient-driven attendance vs A fixed recall interval Outcome NR · Children and adults receiving dental check-ups in primary care, irrespective of oral disease risk Recall intervals for oral health in primary care patients (2020) · Cochrane | No studies identified comparing no-recall/patient-driven attendance with a fixed recall interval. | 0 studies | No studies |
Tetracycline + SRP vs SRP Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Clindamycin + SRP vs Metronidazole + SRP Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Camouflage syringe vs Conventional syringe Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Successful LA/painless treatment: included studies did not report on this outcome | NR | No studies |
Triangular flap vs Envelope flap Temporary altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal · ~1 month Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do) Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · In advance of LA Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Completion of dental treatment: included studies did not report on this outcome | NR | No studies |
Coronectomy vs Complete extraction (odontectomy) Wound infection · Adults with mandibular third molars requiring removal · 1 week Surgical techniques for the removal of mandibular wisdom teeth (2020) · Cochrane | no estimate extracted | NR | No studies |
Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to the patient or HCW before and/or after an AGP vs No treatment or saline or water COVID-19 viral content of aerosol · Patients without suspected or confirmed COVID-19 infection undergoing aerosol-generating procedures (AGPs), and the… Antimicrobial mouthwashes (gargling) and nasal sprays to protect healthcare workers when undertaking… (2020) · Cochrane | No data available (no included studies) | NR | No studies |
The wand (computer-controlled LA delivery system) vs Traditional local anaesthetic Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia · During LA (injection is the intervention) Interventions for increasing acceptance of local anaesthetic in children and adolescents having dental… (2020) · Cochrane | Completion of dental treatment: included studies did not report on this outcome | NR | No studies |
Tetracycline + SRP vs SRP Antimicrobial resistance · Adults with aggressive periodontitis · Long-term (≥ 1 year) Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane | Included studies have not reported this outcome | NR | No studies |
Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced… · mean 2 weeks Interventions for managing halitosis (2019) · Cochrane | Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events. | 0 studies | No studies |
Fixation and stabilisation (splint type/duration) vs Different splint, no splint, or different splinting duration Outcome NR · People with avulsed and replanted permanent (front) teeth Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted (2019) · Cochrane | no estimate extracted | 0 studies | No studies |
Flossing plus toothbrushing vs Toothbrushing alone Interproximal caries · Adults, 16 years and older (dentate) Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane | No included study assessed caries as an outcome. | 0 studies | No studies |
12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs 0 ppm F placebo gel Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond (end of orthodontic treatment) Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane | Additional SoF Table 1. Number of participants with more severe DLs: none of the trials reported this outcome. | 0 studies | No studies |
Wooden cleaning stick plus toothbrushing vs Flossing plus toothbrushing Periodontitis (probing pocket depth) · Adults, 16 years and older (dentate) Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane | No included study assessed periodontitis. | 0 studies | No studies |
Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo) Number of minor postoperative bleeding episodes · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease… (2019) · Cochrane | This outcome was not reported in either of the trials. | 0 studies | No studies |
Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced… · mean 2 weeks Interventions for managing halitosis (2019) · Cochrane | Patient-reported OLT score assessed with patient's perception: listed in the Summary of findings table but no data reported. No data were reported for patient-reported OLT score. | 0 studies | No studies |
Wooden cleaning stick plus toothbrushing vs Toothbrushing alone Gingivitis (gingival index) · Adults, 16 years and older (dentate) Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane | Gingivitis measured by gingival index: Not measured. | 0 studies | No studies |
0.3% triclosan + PVM/MA + sodium fluoride toothpaste vs Sodium fluoride (control) toothpaste Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced… · mean 1 week Interventions for managing halitosis (2019) · Cochrane | Patient-reported OLT score: listed in the Summary of findings table but no data reported. No data were reported for patient-reported OLT score. | 0 studies | No studies |
Hinokitiol gel vs Placebo gel Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced… · mean 4 weeks Interventions for managing halitosis (2019) · Cochrane | Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events. | 0 studies | No studies |
Oral irrigation plus toothbrushing vs Flossing plus toothbrushing Periodontitis (probing pocket depth) · Adults, 16 years and older (dentate) Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane | No included study assessed periodontitis. | 0 studies | No studies |
Patient-used 5000 ppm F toothpaste, daily vs 1450 ppm F (conventional) toothpaste, daily Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond (end of orthodontic treatment) Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane | SoF 3. Number of participants with more severe DLs: none of the trials reported this outcome. | 0 studies | No studies |
Oral hygiene interventions (mechanical plaque removal): knowledge-based, behavioural, or skills training for people with ID or their carers vs Usual care, no care, or a similar alternative intervention Dental caries levels of people with ID · People with intellectual disabilities (ID), living at home, in day care, in hospital or in a residential care setting;… Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane | No studies measured dental caries levels. One RCT (Shaw 1991, Comparison 5) assessed DMFT at baseline only and did not report caries at any later time point. | 0 studies | No studies |
Chlorhexidine + zinc acetate mouthwash vs Placebo mouthwash Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced… · mean 3 months Interventions for managing halitosis (2019) · Cochrane | Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events. | 0 studies | No studies |