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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
7 questions in 1 reviews · cluster CL0352
current versionsNo studies 0 · 0%Ungraded 7 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Higher circulating 25OHD concentration vs Lower circulating 25OHD concentration Alzheimer’s disease · Participants in observational studies Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | SMD (to OR) 0.08 [0.01, 0.63] | 7 studies · 1005 participants | Ungraded |
Higher circulating 25OHD concentration vs Lower circulating 25OHD concentration Aggressive prostate cancer · Participants in observational studies Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | OR 0.98 [0.84, 1.15] | 6 studies · 4524 participants | Ungraded |
Higher circulating 1,25(OH)2D concentration vs Lower circulating 1,25(OH)2D concentration Prostate cancer · Participants in observational studies Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | OR 0.99 [0.87, 1.14] | 7 studies · 3640 participants | Ungraded |
Higher circulating 25OHD concentration vs Lower circulating 25OHD concentration Tuberculosis · Participants in observational studies Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | SMD (to OR) 0.29 [0.19, 0.46] | 7 studies · 534 participants | Ungraded |
Higher circulating 1,25(OH)2D concentration vs Lower circulating 1,25(OH)2D concentration Breast cancer · Participants in observational studies Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | OR 0.99 [0.68, 1.44] | 3 studies · 3627 participants | Ungraded |
Higher circulating 25OHD concentration vs Lower circulating 25OHD concentration Fractures · Participants in observational studies Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | SMD (to OR) 0.31 [0.23, 0.42] | 28 studies · 2956 participants | Ungraded |
Higher circulating 25OHD concentration vs Lower circulating 25OHD concentration All cause mortality (in CKD patients) · Participants in observational studies Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of… (2014) | RR 0.86 [0.81, 0.92] | 10 studies · 6853 participants | Ungraded |