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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
8 questions in 3 reviews · cluster CL0299
current versionsNo studies 1 · 12.5%Ungraded 5 · 62.5%Very low 1 · 12.5%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Consumption of xylitol chewing gum by women (mothers) vs Consumption of CHX/xylitol gum by women, or CHX varnish applied to women's dentition Caries presence in primary teeth · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6… · Children assessed at 4 yrs Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane | RR 0.62 [0.27, 1.39] | 1 study · 96 participants | Very low |
Xylitol syrup (high dose, 8 g/day) vs Control (low-dose xylitol, 2.67 g/day) syrup Caries in primary teeth (mean number of decayed primary teeth) · Infants (primary teeth; baseline about 9 to 15 months) · 12 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | PF 0.58 [0.33, 0.83] | 1 study · 94 participants | Low |
Xylitol chewing gum vs No treatment or non-cariogenic control Outcome NR · Children and adults · At least 1 year Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane | It was surprising that there were no eligible randomised trials testing xylitol chewing gums against either no treatment or a non-cariogenic control. | 0 studies | No studies |
Saliva stimulant lozenge (sorbitol, Sorbee) vs Saliva substitute spray (MouthKote) Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's… Interventions for the management of dry mouth: topical therapies (2011) · Cochrane | Stewart 1998: no statistically significant difference in patient preference between lozenge and spray (Analysis 2.3). | 1 study · 80 participants | Ungraded |
Dentirol chewing gum (xylitol) vs Profylin lozenge (xylitol/sorbitol + CMC) Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's… Interventions for the management of dry mouth: topical therapies (2011) · Cochrane | Patients ranked gum and lozenge equal for preference. | 1 study · 18 participants | Ungraded |
Dentirol chewing gum (xylitol) vs Profylin lozenge (xylitol/sorbitol + CMC) Xerostomia (dry mouth relief) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's… Interventions for the management of dry mouth: topical therapies (2011) · Cochrane | Risheim 1993 (crossover, high risk of bias, n=18, rheumatic patients): both products gave good subjective relief of dry mouth in slightly less than one third of participants; crossover design not accounted for, no… | 1 study · 18 participants | Ungraded |
CMC/sorbitol pre-moistened swabs vs Lemon glycerin swabs Xerostomia (oral dryness) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's… Interventions for the management of dry mouth: topical therapies (2011) · Cochrane | Poland 1987 (crossover, high risk of bias, n=20): CMC/sorbitol reported superior to lemon glycerin for reducing oral dryness; brief report, incomplete data, period effect noted; not usable for meta-analysis. | 1 study · 20 participants | Ungraded |
CMC/sorbitol pre-moistened swabs vs Lemon glycerin swabs Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's… Interventions for the management of dry mouth: topical therapies (2011) · Cochrane | Patient preference favoured CMC/sorbitol (Chi2 10.89, df=1; P = 0.001). | 1 study · 20 participants | Ungraded |