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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
65 questions in 20 reviews · cluster CL0292
current versionsNo studies 4 · 6.2%Ungraded 60 · 92.3%Very low 0 · 0%Low 1 · 1.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Air-abrasive / Vector system debridement vs Manual debridement (carbon fibre curettes) Radiographic marginal bone level · People with at least one dental implant affected by peri-implantitis · 6 months Interventions for replacing missing teeth: treatment of peri‐implantitis (2012) · Cochrane | No statistically significant difference for marginal bone levels; data not usable. | 1 study · 11 participants | Ungraded |
Zirconia abutment vs Titanium abutment Abutment/crown fracture and marginal bone level (3 years) · Patients with single-tooth implant crowns; split-mouth, 3-year · 3 years Interventions for replacing missing teeth: partially absent dentition (2012) · Cochrane | No fractures of any abutments or crowns; non-significant differences in mean marginal bone levels, which ranged from 1.6 to 2.1 mm (narrative) | 1 study · 22 participants | Ungraded |
Immediate implants (placed in a fresh extraction socket just after tooth extraction) vs Delayed implants (placed at least 2 months after extraction, in healed bone) Perimplant marginal bone level changes · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets · 1 year Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate,… (2010) · Cochrane | No statistically significant differences for perimplant marginal bone level changes at 1 year (Lindeboom 2006). | 1 study · 50 participants | Ungraded |
Immediate-delayed implants (placed within 8 weeks after tooth extraction) vs Delayed implants (placed at least 2 months after extraction) Perimplant marginal bone level changes · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets · 2 years Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate,… (2010) · Cochrane | No statistically significant differences for marginal bone level changes (Analysis 2.9; Schropp 2003). | 1 study · 44 participants | Ungraded |
Immediate implants (placed just after tooth extraction) vs Immediate-delayed implants (placed within 8 weeks after tooth extraction) Perimplant marginal bone level changes · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets · 2 years Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate,… (2010) · Cochrane | No statistically significant differences for perimplant marginal bone level changes (Analysis 3.2; Palattella 2008). | 1 study · 16 participants | Ungraded |
Compomer (Dyract) vs Amalgam (Tytin) Marginal integrity (cervical) failures at 24 months · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic… · 24 months Dental fillings for the treatment of caries in the primary dentition (2009) · Cochrane | Marginal integrity (cervical) failures at 24 months: odds ratio not estimable - no events recorded at this interval. | 1 study · 48 participants | Ungraded |
Enamel matrix derivative (EMD; Emdogain) vs Placebo or control (same surgical or non-surgical intervention without EMD) Change in marginal (radiographic) bone level · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony… · 1 year (time-points 1, 5 and 10 years planned) Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects (2009) · Cochrane | No statistically significant difference between EMD and control for radiographic bone gain (three trials; P effect = 0.27, I2 = 78%). | 3 studies | Ungraded |
1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement Radiographic marginal bone level changes · Any subject receiving osseointegrated dental implants · 6 to 12 months after loading Interventions for replacing missing teeth: 1- versus 2-stage implant placement (2009) · Cochrane | MD -0.10 [-0.40, 0.20] | 1 study · 29 participants | Ungraded |
Compomer (Dyract) vs Amalgam (Tytin) Marginal integrity (occlusal) failures at 24 months · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic… · 24 months Dental fillings for the treatment of caries in the primary dentition (2009) · Cochrane | OR 10.76 [0.55, 211.78] | 1 study · 48 participants | Ungraded |
Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler) Change in marginal (radiographic) bone level · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony… · 1 year (time-points 1, 5 and 10 years planned) Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects (2009) · Cochrane | Radiographic bone level: no trial evaluated this. | 0 studies | No studies |
Enamel matrix derivative (EMD; Emdogain) vs Guided tissue regeneration (GTR) with barriers Change in marginal (radiographic) bone level · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony… · 1 year (time-points 1, 5 and 10 years planned) Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects (2009) · Cochrane | No statistically significant differences (one trial). | 1 study | Ungraded |
Direct resin composite veneer vs Indirect resin composite veneer Restoration failure (longevity) · Patients with permanent anterior teeth with intrinsic staining suitable for laminate veneer restorations · 2 years Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Meijering 1998 (data by restoration, not pooled; no statistical analysis possible). Failures over 2-year follow-up: direct resin composite (n=69) 4 absolute and 14 relative failures; indirect resin composite (n=54) 7… | 1 study · 123 participants | Ungraded |
Indirect veneer with no incisal edge reduction vs Indirect veneer with incisal edge reduction (1.5 mm plus short palatal bevel) Restoration survival (longevity) · Patients receiving indirect laminate veneer restorations on permanent anterior teeth · 2 years Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Meijering 1998 (Table 3): survival percentages by preparation type at 2 years (original/functional/overall) - no incisal edge reduction 98/97/95; incisal reduction 95/90/87. No statistical comparison performed. | 1 study | Ungraded |
Direct resin composite veneer vs Porcelain (indirect) veneer Restoration failure (longevity) · Patients with permanent anterior teeth with intrinsic staining suitable for laminate veneer restorations · 2 years Direct versus indirect veneer restorations for intrinsic dental stains (2004) · Cochrane | Meijering 1998 (data by restoration, not pooled; no statistical analysis possible). Failures over 2-year follow-up: direct resin composite (n=69) 4 absolute and 14 relative failures; porcelain (n=56) 0 absolute and 3… | 1 study · 125 participants | Ungraded |
Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO) Dissatisfied with retention of denture · Edentulous patients requiring improved denture retention · 1 year Interventions for replacing missing teeth: preprosthetic surgery versus dental implants (2002) · Cochrane | RR 2.41 [0.84, 6.95] | 1 study · 58 participants | Ungraded |