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Evidence found and GRADE certainty

486 questions · 503 findings · 36 reviews · Oral and maxillofacial surgery · related questions CL0289

No studies found 116 · 23.1%GRADE not reported 303 · 60.2%Very low 66 · 13.1%Low 12 · 2.4%Moderate 2 · 0.4%High 4 · 0.8%

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo

Outcome not reported · Immunosuppressed / immunocompromised patients (e.g. HIV infection, AIDS, diabetes, transplants) undergoing tooth extraction

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

Fever · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes fever (6th-7th day) compared with placebo (very low certainty).

1 finding from 1 review

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo

Outcome not reported · Patients undergoing tooth extraction for severe dental caries or periodontal disease in general dental practice (non-third-molar / decayed…

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies in general dental practice for removal of decayed teeth. PUB3 added one routine intra-alveolar extraction trial and one complex oral surgery trial (2 of 23 non-third-molar), but the single intra-alveolar…
    0 studies
    No studies found

Absence (previous removal or agenesis) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Caries affecting the (distal) adjacent second molar · Adults (416 healthy male volunteers aged 24 to 84 years) with asymptomatic disease-free impacted wisdom teeth

It is very uncertain whether absence (previous removal or agenesis) of asymptomatic disease-free… changes caries affecting the (distal) adjacent second molar compared with presence (retention) of asymptomatic disease-free impacted wisdom… (very low certainty).

2 findings from 1 review

Drain use vs No drain

Maximal mouth opening (interincisal distance) · Adults with mandibular third molars requiring removal

Surgical drain (tube or gauze) led to higher maximum mouth opening (mean) compared with no drain; GRADE not reported.

1 finding from 1 review

Drain use vs No drain

Postoperative pain (mean) · Adults with mandibular third molars requiring removal

Surgical drain (tube or gauze) showed no clear difference in postoperative pain (mean) compared with no drain; GRADE not reported.

1 finding from 1 review

Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional)

Swelling (mean) · Adults with mandibular third molars requiring removal

Autologous platelet concentrate (PRP/PRF) in socket showed no clear difference in swelling (mean) compared with no blood product (conventional); GRADE not reported.

1 finding from 1 review