Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Removable functional appliance vs Fixed functional appliance

Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Ball (stud) attachment system vs Telescopic attachment system

Prosthodontic maintenance: reline of implant overdenture (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)

It is very uncertain whether ball (stud) attachment system changes prosthodontic maintenance: reline of implant overdenture (short term) compared with telescopic attachment system (very low certainty).

1 finding from 1 review

Orthodontic treatment without extraction of permanent teeth vs No treatment (or delayed treatment)

Dento-occlusal results of treatment, measured with the PAR index · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)

The review found no eligible studies for this question.

1 finding from 1 review

GTR rm associated with bone substitutes + CAF vs SCTG + CAF

Keratinized tissue width change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

GTR rm associated with bone substitutes + CAF led to lower keratinized tissue width change compared with SCTG + CAF; GRADE not reported.

1 finding from 1 review

0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Success of local anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

0.5% bupivacaine, 1:200,000 epinephrine showed no clear difference in success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

Activator functional appliance vs Fixed functional appliance (FORSUS FRD EZ)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Activator functional appliance led to higher final overjet compared with fixed functional appliance (FORSUS FRD EZ); GRADE not reported.

1 finding from 1 review

Early treatment (two-phase) with headgear vs Late treatment (one-phase in adolescence) with headgear

Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear led to lower final ANB compared with late treatment (one-phase in adolescence) with headgear; GRADE not reported.

2 findings from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Non-rinse conditioner + acetone-based total-etch adhesive

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Speed of onset of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:100,000 epinephrine changes speed of onset of anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review

0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Success of local anaesthesia (soft tissue, self-reported; 100% success in all studies) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review
  • 'Other comparisons with 100% success': IANB - Sampaio 2012 35/35 vs 35/35; Fernandez 2005 39/39 vs 39/39. Both formulations 100% successful; no meta-analysis (no difference).
    2 studies · 74 participants
    GRADE not reported

GTR rm associated with bone substitutes + CAF vs GTR rm + CAF

Aesthetic condition change related to patient's opinion · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

The review found no eligible studies for this question.

1 finding from 1 review

Late treatment (one-phase) with removable functional appliance vs no treatment

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Late treatment (one-phase) with removable functional appliance may leads to lower final overjet compared with no treatment (low certainty).

1 finding from 1 review