Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final ANB compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.
2 findings from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Portland cement (PC) showed no clear difference in clinical failure compared with enamel matrix derivative (EMD); GRADE not reported.
1 finding from 1 review
Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)
It is very uncertain whether 10% CP gel in tray (with desensitiser) changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).
1 finding from 1 review
Speed of onset of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
4% prilocaine, 1:200,000 epinephrine showed no clear difference in speed of onset of anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).
1 finding from 1 review
Speed of onset of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review
SoF: See comment, not estimable (orphan study; duration of follow-up not reported); 100 participants, 100 interventions (1 study). Not pooled/graded.
1 study · 100 participants
GRADE not reported
Success of local anaesthesia, absence of pain (clinical testing of healthy pulps, hard and soft tissues) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
4% articaine, 1:100,000 epinephrine showed no clear difference in success of local anaesthesia, absence of pain (clinical testing of… compared with 2% mepivacaine, 1:100,000 epinephrine (low certainty).
1 finding from 1 review
Speed of onset of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
4% prilocaine plain showed no clear difference in speed of onset of anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).
1 finding from 1 review
Patient discomfort · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Abutment mobility · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture
It is very uncertain whether altered-cast impression technique (ACIP), polyether changes abutment mobility compared with one-piece cast technique (OPC), polyether (very low certainty).
2 findings from 1 review
RR 1.16 [0.40, 3.37]
1 study
Very low
RR 2.90 [0.87, 9.61]
1 study
Very low
Prosthodontic maintenance: matrix activated (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
It is very uncertain whether ball (stud) attachment system changes prosthodontic maintenance: matrix activated (short term) compared with telescopic attachment system (very low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with sodium hypochlorite (NaOCl); GRADE not reported.
1 finding from 1 review
Antifibrinolytic agents (tranexamic acid (TXA) or epsilon aminocaproic acid (EACA)) vs Placebo, no intervention, or usual care
Outcome not reported · People on continuous direct oral anticoagulant (DOAC) treatment undergoing oral or dental procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Success of local anaesthesia (soft tissue, self-reported; 100% success in all studies) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review
Development and eruption of the second permanent molar · Children aged 5 to 15 years with a compromised first permanent molar
Root closure and eruption of the second permanent molar appeared accelerated on the extraction side in a single case-control study; ungraded and not statistically tested.
1 finding from 1 review
Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)
The review found no eligible studies for this question.
1 finding from 1 review
Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)
It is very uncertain whether 15% CP gel in tray changes tooth whitening - assessed by the dentist compared with 10% CP gel in tray (very low certainty).
1 finding from 1 review
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
It is very uncertain whether nitrous oxide/oxygen changes behaviour (Houpt/behavioural score) compared with placebo (including no intervention) (very low certainty).
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in probing depth (PD) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.92 [-0.02, 1.86]
7 studies · 248 participants
Very low
MD 1.07 [-0.71, 2.86]
3 studies · 134 participants
GRADE not reported
MD 0.68 [-0.66, 2.02]
5 studies · 164 participants
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Tempophore showed no clear difference in clinical failure compared with mineral trioxide aggregate (MTA); GRADE not reported.
1 finding from 1 review
Success of local anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
4% articaine, 1:100,000 epinephrine may leads to higher success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).
1 finding from 1 review