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What do systematic reviews say?

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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method

Maxillary denture satisfaction · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes maxillary denture satisfaction compared with two stage-two step elastomer (silicone, polysulfide, or polyether)… (very low certainty).

1 finding from 1 review

Fixed functional appliance (FORSUS FRD) vs Intermaxillary elastics

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Fixed functional appliance (FORSUS FRD) showed no clear difference in final ANB compared with intermaxillary elastics; GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Buffered glutaraldehyde

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, pulp canal obliteration (Goyal 2016); no clinical/radiological failure outcome; pain, mobility, radiolucency, root resorption significantly favour MTA
    1 study · 60 participants
    GRADE not reported

Mineral trioxide aggregate (MTA) vs Diode laser

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, premature tooth loss (Niranjani 2015); no clinical/radiological failure outcome; no significant differences (RR 0.33, 0.01 to 7.72)
    1 study · 40 participants
    GRADE not reported

ProRoot MTA vs RetroMTA

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

ProRoot MTA showed no clear difference in radiological failure compared with retroMTA; GRADE not reported.

1 finding from 1 review

5.9% HP strip vs 5.9% HP paint-on gel

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

5.9% HP strip led to higher tooth whitening - assessed by the dentist compared with 5.9% HP paint-on gel; GRADE not reported.

2 findings from 1 review

5% CP gel in tray vs 10% CP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 5% CP gel in tray changes tooth whitening - assessed by the dentist compared with 10% CP gel in tray (very low certainty).

1 finding from 1 review

EMP + CAF vs CAF

Attachment change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

EMP + CAF showed no clear difference in clinical attachment level change compared with CAF (low certainty).

2 findings from 1 review