Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether azithromycin + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).
3 findings from 1 review
MD -0.59 [-1.27, 0.08]
2 studies · 110 participants
Very low
MD -0.43 [-0.77, -0.10]
7 studies · 258 participants
GRADE not reported
MD -0.51 [-0.83, -0.19]
6 studies · 216 participants
GRADE not reported
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults with chronic periodontitis
Moxifloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Moxifloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Clarithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
2 findings from 1 review
Percentage of closed pockets · Adults with chronic periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in probing pocket depth compared with amoxicillin + metronidazole + SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.
3 findings from 1 review
MD 0.04 [-0.43, 0.50]
4 studies · 108 participants
GRADE not reported
MD -1.12 [-2.24, 0.00]
3 studies · 71 participants
Very low
MD -0.49 [-1.29, 0.31]
4 studies · 94 participants
GRADE not reported
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Levofloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in probing pocket depth compared with tetracycline + SRP; GRADE not reported.
1 finding from 1 review
MD -0.40 [-1.11, 0.31]
1 study · 8 participants
GRADE not reported
Percentage of closed pockets · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in probing pocket depth compared with SRP; GRADE not reported.
1 finding from 1 review
Plaque · Medically healthy individuals (adults and children, 6-60 years)
Placebo rinse did not significantly change plaque relative to baseline; not GRADE-rated.
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in probing depth (PD) (mm) compared with OFD (open flap debridement) alone (very low certainty).
1 finding from 1 review
Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
Autologous platelet concentrates (APC) + open flap debridement (OFD)… led to higher change in radiographic bone defect filling (RBF) (%) compared with OFD + BG (open flap debridement + bone graft); GRADE not reported.
3 findings from 1 review
MD 9.99 [6.44, 13.55]
6 studies · 282 participants
GRADE not reported
MD 4.76 [1.27, 8.25]
6 studies · 162 participants
GRADE not reported
MD 8.10 [5.26, 10.94]
11 studies · 420 participants
Very low
Plaque · Dentate adults without severe periodontitis, regularly attending for dental care in primary care (UK general dental practice)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in clinical attachment level (CAL) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.42 [-0.02, 0.86]
7 studies · 248 participants
Very low
MD 0.27 [-0.39, 0.93]
5 studies · 164 participants
GRADE not reported
MD 0.54 [0.18, 0.89]
3 studies · 134 participants
GRADE not reported