Pain at 48 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)
Postoperative systemic antibiotics… showed no clear difference in pain at 48 hours compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.
1 finding from 1 review
Severity of joint noise · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes severity of joint noise compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).
1 finding from 1 review
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) showed no clear difference in wits appraisal compared with pushing Splints; GRADE not reported.
1 finding from 1 review
Pain · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
Different sizes of NiTi wires (Alhaija 2021; Erdinc 2004); not pooled due to clinical heterogeneity; little or no difference at day 1. Erdinc 0.014 vs 0.016 inch higher pain at day 4 MD 5.00 (0.19 to 9.81) and day 6 MD…
2 studies · 149 participants
Low
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with behavioural therapy (counselling, CBT, relaxation, self-care… (very low certainty).
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether abdominal dermal fat graft changes maximal mouth opening (interincisal distance) compared with nasolabial flap (very low certainty).
2 findings from 1 review
MD -14.87 [-19.93, -9.81]
1 study · 30 participants
Very low
MD -3.60 [-5.17, -2.03]
1 study · 30 participants
Very low
Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
It is very uncertain whether thermoelastic copper NiTi (CuNiTi) arch wire changes alignment rate compared with conventional NiTi arch wire (very low certainty).
1 finding from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask probably leads to higher ANB compared with untreated control (no treatment) (moderate certainty).
3 findings from 1 review
MD 1.40 [0.43, 2.37]
1 study · 63 participants
Moderate
MD 0.70 [-0.74, 2.14]
1 study · 65 participants
Low
MD 3.60 [2.68, 4.52]
5 studies · 197 participants
GRADE not reported
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether vasodilators (isoxsuprine, xanthinol nicotinate) changes burning sensation (VAS 0-100) compared with placebo or no active treatment (very low certainty).
2 findings from 1 review
MD -51.02 [-72.85, -29.20]
2 studies · 85 participants
Very low
MD -38.79 [-52.06, -25.53]
2 studies · 85 participants
Very low
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether topical curcumin gel changes burning sensation (VAS 0-100) compared with topical aloe vera gel (very low certainty).
1 finding from 1 review
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask (RME) or modified facemask showed no clear difference in wits appraisal compared with surgically-anchored appliance (miniscrews or miniplates); GRADE not reported.
1 finding from 1 review
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) showed no clear difference in overjet compared with pushing Splints; GRADE not reported.
1 finding from 1 review
Intolerance to spicy food (participant-reported proxy) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Antioxidants (lycopene, curcumin, Oxitard) led to lower intolerance to spicy food (participant-reported proxy) compared with placebo or no active treatment; GRADE not reported.
1 finding from 1 review
Muscle pain when chewing · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain when chewing compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Pain at 72 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)
It is very uncertain whether postoperative systemic antibiotics… changes pain at 72 hours compared with matched placebo, partial or total chemo-mechanical debridement and… (very low certainty).
1 finding from 1 review
Self-esteem (Oral Aesthetic Subjective Impact Score, OASIS) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask led to lower self-esteem (Oral Aesthetic Subjective Impact Score, OASIS) compared with untreated control (no treatment); GRADE not reported.
3 findings from 1 review
MD -4.00 [-7.40, -0.60]
1 study · 69 participants
GRADE not reported
MD -2.20 [-7.31, 2.91]
1 study · 65 participants
GRADE not reported
MD -3.40 [-7.99, 1.19]
1 study · 63 participants
GRADE not reported
Patient discomfort · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Pain day 1 · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
Superelastic NiTi arch wire showed no clear difference in pain day 1 compared with conventional (stabilised) NiTi arch wire (low certainty).
1 finding from 1 review
Muscle pain when chewing · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with another occlusal splint with a different mechanism of action (very low certainty).
1 finding from 1 review