Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Clindamycin + SRP vs SRP

Clinical attachment level (CAL) · Adults with aggressive periodontitis

Clindamycin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.

3 findings from 1 review

One type of dental check-up (e.g. examination plus scale and polish) vs A different type of dental check-up (e.g. examination only) at the same fixed recall interval

Outcome not reported · Children and adults receiving dental check-ups in primary care, irrespective of oral disease risk

The review found no eligible studies for this question.

1 finding from 1 review

Doxycycline + SRP vs Amoxicillin + metronidazole + SRP

Clinical attachment level (CAL) · Adults with aggressive periodontitis

Doxycycline + SRP showed no clear difference in clinical attachment level (CAL) compared with amoxicillin + metronidazole + SRP; GRADE not reported.

2 findings from 1 review

Clarithromycin + SRP vs SRP

Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)

Clarithromycin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.

2 findings from 1 review

Video modelling acclimatisation for LA vs Oral hygiene video

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: anxiety/pain experience (VAS, higher scores indicate worsened anxiety) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

Video modelling acclimatisation for LA may leads to lower self- or observational assessment of intraoperative… compared with oral hygiene video (low certainty).

1 finding from 1 review

Absence (previous removal or agenesis) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Caries affecting the (distal) adjacent second molar · Adults (416 healthy male volunteers aged 24 to 84 years) with asymptomatic disease-free impacted wisdom teeth

It is very uncertain whether absence (previous removal or agenesis) of asymptomatic disease-free… changes caries affecting the (distal) adjacent second molar compared with presence (retention) of asymptomatic disease-free impacted wisdom… (very low certainty).

2 findings from 1 review

Video modelling acclimatisation for LA vs Oral hygiene video

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Oral health behaviour (1-9 scale) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in oral health behaviour (1-9 scale) compared with clinical examination with 24-month recall; GRADE not reported.

1 finding from 1 review

Systemic (oral) betamethasone vs Topical triamcinolone acetonide paste

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether systemic (oral) betamethasone changes clinical score compared with topical triamcinolone acetonide paste (very low certainty).

1 finding from 1 review

Metronidazole + SRP vs Amoxicillin + metronidazole + SRP

Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)

Metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with amoxicillin + metronidazole + SRP; GRADE not reported.

2 findings from 1 review

Counter-stimulation and distraction (combined) vs Conventional treatment

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA (SEM scale, distress) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
1 finding from 1 review

Doxycycline + SRP vs Amoxicillin + metronidazole + SRP

Probing pocket depth · Adults with aggressive periodontitis

Doxycycline + SRP showed no clear difference in probing pocket depth compared with amoxicillin + metronidazole + SRP; GRADE not reported.

2 findings from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Patient satisfaction with actual care received (1-7 scale) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in patient satisfaction with actual care received (1-7 scale) compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review