Maximum pain while on medication (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Topical capsaicin (0.025% cream) showed no clear difference in maximum pain while on medication (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral naproxen (NSAID) led to lower pain intensity (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Aesthetics assessed by dentist: position of the perimplant tissues · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate implants (placed in a fresh extraction socket just after… led to lower aesthetics assessed by dentist: position of the perimplant tissues compared with delayed implants (placed at least 2 months after extraction, in…; GRADE not reported.
1 finding from 1 review
One year after placement, there were no statistically significant differences for the level of the perimplant marginal mucosa in relation to that of the adjacent teeth (Lindeboom 2006).
1 study · 50 participants
GRADE not reported
Tenderness on palpation of three or more masticatory muscles · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral diclofenac sodium (NSAID) showed no clear difference in tenderness on palpation of three or more masticatory muscles compared with placebo; GRADE not reported.
1 finding from 1 review
Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Resorbable barrier (guided bone regeneration) led to lower major complications at the implant/donor site compared with non-resorbable barrier (guided bone regeneration); GRADE not reported.
1 finding from 1 review
Four complications occurred: two dehiscences in the resorbable group; one abscess and one dehiscence in the resorbable + autogenous bone group; none in the non-resorbable group. No statistically significant differences…
1 study · 23 participants
GRADE not reported
Prosthesis failure · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… led to lower prosthesis failure compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower major complications at the implant/donor site compared with no augmentation; GRADE not reported.
1 finding from 1 review
Two complications occurred in the group treated with autogenous bone (one abscess that determined the early failure of the implant and one wound dehiscence); none in the control group.
1 study · 26 participants
GRADE not reported
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in pain intensity (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Severe or very severe symptoms · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral diclofenac sodium (NSAID) showed no clear difference in severe or very severe symptoms compared with placebo; GRADE not reported.
1 finding from 1 review
Present pain of TMD (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Topical capsaicin (0.025% cream) showed no clear difference in present pain of TMD (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Number of participants with severe dysfunction (pain of TMD not improved) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral diazepam (benzodiazepine) showed no clear difference in number of participants with severe dysfunction (pain of TMD not… compared with placebo; GRADE not reported.
1 finding from 1 review
Implant failure · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate implants (placed in a fresh extraction socket just after… showed no clear difference in implant failure compared with delayed implants (placed at least 2 months after extraction, in…; GRADE not reported.
1 finding from 1 review
Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (vertical - VDH) compared with no augmentation; GRADE not reported.
1 finding from 1 review
Both treatments resulted in statistically significant bone gain, however no statistically significant differences were found between the two procedures for vertical height of the defect (VDH) (Chen 2005b).
1 study · 26 participants
GRADE not reported
Satisfaction with treatment ‐ general · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… led to higher patients' general satisfaction of treatment compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Poor aesthetics measured by patient (after restoration) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by patient (after restoration) compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
Patients' perception of how long treatment took · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… led to lower patients' perception of how long treatment took compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (horizontal - HDD) compared with no augmentation; GRADE not reported.
1 finding from 1 review
Development of TMD (onset/incidence of signs and symptoms) · People without TMD at baseline undergoing orthodontic treatment (TMD clinically absent at baseline); no age restriction provided follow-up…
The review found no eligible studies for this question.
1 finding from 1 review
Overall symptoms, pain and headache (relief from symptoms assessed by global measures) · Adults aged 18 years or older with clinically diagnosed TMD (exhibiting two or more of the listed signs and/or symptoms)
The review found no eligible studies for this question.
1 finding from 1 review
Augmentation (prosthesis/implant) failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower augmentation (prosthesis/implant) failure compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review