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Evidence found and GRADE certainty

488 questions · 529 findings · 33 reviews · Orthodontics · related questions CL0289

No studies found 117 · 22.1%GRADE not reported 263 · 49.7%Very low 65 · 12.3%Low 60 · 11.3%Moderate 21 · 4%High 3 · 0.6%

NSAID (systemic) vs paracetamol

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

NSAID (systemic) showed no clear difference in pain intensity (VAS 0-100 mm) compared with paracetamol (low certainty).

3 findings from 1 review

Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control

Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review

Bonded molar tubes (attached with adhesive) vs Molar bands (cemented, e.g. with glass ionomer cement)

Decalcification · Participants with full arch fixed orthodontic appliance(s) with molar tubes bonded to first or second permanent molars; excludes prior…

Bonded molar tubes (attached with adhesive) led to higher decalcification (participant level) compared with molar bands (cemented, e.g. with glass ionomer cement); GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Patient response: total discomfort score (pain, difficulty eating, brushing, speaking, bad taste) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in patient response: total discomfort score (pain, difficulty eating,… compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Topical NSAID (ketoprofen chewing gum) vs Local anaesthetic (benzocaine chewing gum)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

It is very uncertain whether topical NSAID (ketoprofen chewing gum) changes pain intensity (VAS 0-100 mm) compared with local anaesthetic (benzocaine chewing gum) (very low certainty).

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Aesthetics: canine rated as abnormal tooth inclination · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in aesthetics: canine rated as abnormal tooth inclination compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Patient response: moderate or severe pain at 1 day postoperative · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in patient response: moderate or severe pain at 1 day postoperative compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Treatment time: duration of orthodontic treatment (placement to removal of fixed appliances) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in treatment time: duration of orthodontic treatment (placement to… compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Patient response: satisfaction with treatment (satisfactory vs unsatisfactory) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in patient response: satisfaction with treatment (satisfactory vs… compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Bonded molar tubes (attached with adhesive) vs Molar bands (cemented, e.g. with glass ionomer cement)

First time failure at participant level · Participants with full arch fixed orthodontic appliance(s) with molar tubes bonded to first or second permanent molars; excludes prior…

Bonded molar tubes (attached with adhesive) led to higher first time failure at participant level compared with molar bands (cemented, e.g. with glass ionomer cement); GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Aesthetics: canine rated as abnormal tooth colour · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in aesthetics: canine rated as abnormal tooth colour compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Success of surgery (eruption of the canine crown sufficient for orthodontic alignment, without repeated surgery) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in success of surgery (eruption of the canine crown sufficient for… compared with closed surgical exposure (low certainty).

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Treatment time: length of time in the operating theatre (first incision to final suture) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

It is very uncertain whether open surgical exposure changes treatment time: length of time in the operating theatre (first… compared with closed surgical exposure (very low certainty).

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Gum health: radiographic crestal bone level · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in gum health: radiographic crestal bone level compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review