Presence/absence of HSV oral lesions · Patients being treated for cancer (acute leukaemia; chemotherapy or stem-cell transplantation)
Prophylactic valaciclovir (lower dose) showed no clear difference in presence/absence of HSV oral lesions compared with prophylactic valaciclovir (higher dose); GRADE not reported.
1 finding from 1 review
Experienced the operation negatively · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… showed no clear difference in experienced the operation negatively compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
Length of hospital stay · Patients being treated for cancer with established oral HSV infection (bone marrow transplant recipients / immunocompromised)
The review found no eligible studies for this question.
1 finding from 1 review
For the treatment comparison (aciclovir versus placebo), no data were available for recurrence of lesions, amount of analgesia, days of stay in hospital, cost of oral care or patient quality of life.
0 studies
No studies found
Implant failure · Patients with atrophic posterior mandibles (5 to 7 mm above the mandibular canal) needing implants
Inlay autogenous bone graft (iliac crest) showed no clear difference in implant failure compared with inlay bone substitute (Bio-Oss block); GRADE not reported.
1 finding from 1 review
Prosthesis failure · People with dental implants
1-stage (non-submerged) implant placement showed no clear difference in prosthesis failure compared with 2-stage (submerged) implant placement (moderate certainty).
1 finding from 1 review
Marginal bone level change · Patients with vertically deficient posterior/anterior mandibular ridges needing implants
Vertical distraction osteogenesis showed no clear difference in 1-year post-loading bone level changes compared with autogenous onlay bone graft (mandibular ramus); GRADE not reported.
2 findings from 1 review
Viral isolates (HSV isolates identified, with or without clinical symptoms) · Patients being treated for cancer (predominantly haematological malignancies)
Prophylactic aciclovir (oral or intravenous) led to lower viral isolates (HSV isolates identified, with or without clinical… compared with placebo; GRADE not reported.
1 finding from 1 review
Degree of function postoperatively (mastication, swallowing, speech) · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…
The review found no eligible studies for this question.
1 finding from 1 review
Cervical gaps on bitewing X-rays at 24 months · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free
Compomer (Dyract) showed no clear difference in cervical gaps on bitewing X-rays at 24 months compared with amalgam (Tytin); GRADE not reported.
1 finding from 1 review
Aesthetics · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
The review found no eligible studies for this question.
1 finding from 1 review
Amount of analgesia · Patients being treated for cancer with established oral HSV infection (bone marrow transplant recipients / immunocompromised)
The review found no eligible studies for this question.
1 finding from 1 review
For the treatment comparison (aciclovir versus placebo), no data were available for recurrence of lesions, amount of analgesia, days of stay in hospital, cost of oral care or patient quality of life.
0 studies
No studies found
Major complications · Patients with atrophic posterior mandibles (5 to 7 mm above the mandibular canal) needing implants
Inlay autogenous bone graft (iliac crest) showed no clear difference in major complications compared with inlay bone substitute (Bio-Oss block); GRADE not reported.
1 finding from 1 review
Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Overall success (compound score combining pain and MIO) · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…
Arthrocentesis and lavage showed no clear difference in overall success (compound score combining pain and MIO) compared with arthroscopy; GRADE not reported.
1 finding from 1 review
Viral isolates · Patients being treated for cancer (acute leukaemia; chemotherapy or stem-cell transplantation)
1 finding from 1 review
Orlowski 2004: 182 throat swabs performed for patients receiving 500 mg of valaciclovir (n = 40) and 198 swabs for those receiving 1000 mg (n = 41); all of the cultures proved negative (1 trial, 81; not estimable).
1 study · 81 participants
GRADE not reported
Presence/absence of HSV oral lesions · Patients being treated for cancer (predominantly haematological malignancies)
Prophylactic aciclovir (oral or intravenous) showed no clear difference in presence/absence of HSV oral lesions compared with prophylactic valaciclovir (oral); GRADE not reported.
1 finding from 1 review
Denture plaque · Wearers of maxillary and mandibular complete dentures (CD)
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in probing pocket depth (PPD) compared with guided tissue regeneration (GTR) with barriers (low certainty).
1 finding from 1 review
Prosthesis/implant failure (1 year) · Patients with horizontally resorbed maxillary sites needing single implants
Autogenous bone block from the chin + resorbable barrier showed no clear difference in prosthesis/implant failure (1 year) compared with 100% Bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
Visual plaque score · Complete denture (CD) wearers
Silicone surfactant cleanser led to lower visual plaque score compared with placebo / sham solution; GRADE not reported.
2 findings from 1 review
MD -0.88 [-1.00, -0.76]
1 study
GRADE not reported
MD -1.02 [-1.13, -0.91]
1 study
GRADE not reported