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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Enzyme cleanser vs Brushing

Denture plaque · Wearers of maxillary and mandibular complete dentures (CD)
1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    Standard deviations were not reported for the relevant data so these were not included in the analysis. Reduction of plaque scores was associated with enzyme concentration (ANOVA, P < 0.001). Brushing alone and…
    1 study
    GRADE not reported

Enamel matrix derivative (EMD; Emdogain) vs Guided tissue regeneration (GTR) with barriers

Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in probing pocket depth (PPD) compared with guided tissue regeneration (GTR) with barriers (low certainty).

1 finding from 1 review

Autogenous bone block from the chin + resorbable barrier vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Prosthesis/implant failure (1 year) · Patients with horizontally resorbed maxillary sites needing single implants

Autogenous bone block from the chin + resorbable barrier showed no clear difference in prosthesis/implant failure (1 year) compared with 100% Bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Silicone surfactant cleanser vs Placebo / sham solution

Visual plaque score · Complete denture (CD) wearers

Silicone surfactant cleanser led to lower visual plaque score compared with placebo / sham solution; GRADE not reported.

2 findings from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Complication at augmented site · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in complication at augmented site compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

No improvement of facial appearance (3 weeks) · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to lower no improvement of facial appearance (3 weeks) compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review

Horizontal bone augmentation (any technique) vs No augmentation

Outcome not reported · Patients with horizontally resorbed maxillary sites needing single implants

The review found no eligible studies for this question.

1 finding from 1 review

Arthrocentesis and lavage vs Arthroscopy

Temporomandibular joint tenderness · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic aciclovir (oral or intravenous) vs placebo

Presence/absence of HSV oral lesions · Patients being treated for cancer (predominantly haematological malignancies)

Prophylactic aciclovir (oral or intravenous) led to lower presence/absence of HSV oral lesions compared with placebo; GRADE not reported.

1 finding from 1 review

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

Prosthetic failure (2 years) · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… showed no clear difference in prosthetic failure compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review

Enzyme cleanser vs Placebo / sham solution

Improvement on denture cleanliness (caregivers' opinion) · Institutionalised elderly wearing maxillary complete dentures (CD)

Enzyme cleanser led to lower improvement on denture cleanliness (caregivers' opinion) compared with placebo / sham solution; GRADE not reported.

1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    12 weeks
    After 12 weeks using an enzyme denture cleanser ('E'), 8 of 18 caregivers perceived some improvement in CD cleanliness. After using a placebo solution ('Plac'), only 2 of 17 perceived some improvement (Analysis 1.1,…
    1 study · 35 participants
    GRADE not reported

Ultrasound during vertical distraction osteogenesis vs Placebo (no ultrasound) during vertical distraction

Distraction distance (bone gain, mm) · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Ultrasound during vertical distraction osteogenesis showed no clear difference in distraction distance (bone gain, mm) compared with placebo (no ultrasound) during vertical distraction; GRADE not reported.

1 finding from 1 review

Arthrocentesis and lavage vs Arthroscopy

Deviation of the mandible · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

The review found no eligible studies for this question.

1 finding from 1 review

Effervescent tablets vs Association of brushing and effervescent tablets

Total anaerobes (colony forming units, log-transformed) · Maxillary complete denture (CD) wearers

Effervescent tablets showed no clear difference in total anaerobes (colony forming units, log-transformed) compared with association of brushing and effervescent tablets; GRADE not reported.

1 finding from 1 review

Prophylactic aciclovir (oral or intravenous) vs placebo

Length of hospital stay · Patients being treated for cancer (predominantly haematological malignancies)

The review found no eligible studies for this question.

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing pocket depth (PPD) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Vertical distraction osteogenesis vs Autogenous inlay bone graft (iliac crest)

Vertical bone gain · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical distraction osteogenesis led to higher vertical bone gain compared with autogenous inlay bone graft (iliac crest); GRADE not reported.

1 finding from 1 review

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

Major complications · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to higher major complications compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

Patient preference including aesthetics (split-mouth studies only) · People with dental implants

The review found no eligible studies for this question.

1 finding from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Perimplant bone loss · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in perimplant bone loss (3 years) compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review