Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
Donatsky 1982 (crossover, n=15, Sjogren's syndrome): CMC spray had a similar effect on oral dryness to the spray base, but was more effective than water. Paired crossover data not presented; effect size not estimable.
1 study · 15 participants
GRADE not reported
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Camomile showed no clear difference in oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Clinical assessment: alveolar ridge healing (0 to 3 grading scale) · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)
Artificial bone graft: InFuse (collagen matrix) impregnated with… led to higher clinical assessment: alveolar ridge healing (0 to 3 grading scale) compared with traditional iliac crest cancellous bone graft; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Indigo wood root showed no clear difference in oral mucositis (moderate to severe) compared with saline (placebo); GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Sucralfate showed no clear difference in oral mucositis (any severity) compared with placebo/usual care (moderate certainty).
1 finding from 1 review
Secondary alveolar bone grafting performed at one timing (e.g. early secondary grafting) vs Secondary alveolar bone grafting performed at a different / optimal timing (e.g. late secondary grafting)
Outcome not reported · Patients greater than 5 years of age with unilateral or bilateral cleft lip and/or palate involving the alveolar process (complete or…
The review found no eligible studies for this question.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Intestinal trefoil factor showed no clear difference in oral mucositis (severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral health (oral impacts on daily performances) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
More in the reservoir group experienced relief of an oral impact and fewer a new impact (OIDP), but no difference in the total impact score between groups.
1 study · 86 participants
GRADE not reported
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Zinc sulphate led to lower oral mucositis (severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Glutamine showed no clear difference in oral mucositis (any severity) compared with placebo/usual care; GRADE not reported.
1 finding from 1 review
RR 0.78 [0.57, 1.08]
5 studies
GRADE not reported
Radiographic assessment: periapical film (0 to 3 grading scale) · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)
Artificial bone graft: InFuse (collagen matrix) impregnated with… led to higher radiographic assessment: periapical film (0 to 3 grading scale) compared with traditional iliac crest cancellous bone graft; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Polaprezinc led to lower oral mucositis (moderate to severe) compared with azulene; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Sucralfate probably leads to lower oral mucositis (severe) compared with placebo/usual care (moderate certainty).
1 finding from 1 review
Energy and protein intake · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…
1 finding from 1 review
Mean energy and protein intakes (Brine 1994): statistically significant difference for protein intake at 3 and 6 months in favour of the squeezable bottle (P < 0.05); possibly confounded by four infants receiving a…
1 study · 37 participants
GRADE not reported
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Polaprezinc showed no clear difference in oral mucositis (any severity) compared with azulene; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Shenqi-fanghou led to lower oral mucositis (severe) compared with no treatment; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Keratinocyte GF led to lower oral mucositis (moderate to severe) compared with placebo; GRADE not reported.
1 finding from 1 review
RR 0.74 [0.62, 0.89]
7 studies
GRADE not reported
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Histamine gel showed no clear difference in oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
No significant difference in patient preference between the treatments (Chi2 3.67, df=3; P = 0.30).
1 study · 123 participants
GRADE not reported
Tenderness on palpation in jaw muscles (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…
Arthroscopy showed no clear difference in tenderness on palpation in jaw muscles (clinical evaluation, 12… compared with open surgery; GRADE not reported.
1 finding from 1 review