Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Oral care protocol showed no clear difference in oral mucositis (severe) compared with no treatment/usual care; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Cryotherapy (ice chips) 30 minutes showed no clear difference in oral mucositis (any severity) compared with cryotherapy (ice chips) 60 minutes; GRADE not reported.
1 finding from 1 review
Anxiety · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))
Hypnosis showed no clear difference in anxiety (short term) compared with relaxation; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Pentoxifylline showed no clear difference in oral mucositis (moderate to severe) compared with no treatment; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Glutamine showed no clear difference in oral mucositis (moderate to severe) compared with placebo/usual care; GRADE not reported.
1 finding from 1 review
RR 0.88 [0.69, 1.12]
5 studies
GRADE not reported
Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
Mucin-containing lozenge showed no clear difference in xerostomia (VAS mouth dryness) compared with placebo lozenge; GRADE not reported.
1 finding from 1 review
Gravenmade 1993 (crossover, high risk of bias, n=42, Sjogren's syndrome): no statistically significant difference between mucin lozenge and placebo for mouth dryness on a VAS (Analysis 1.2).
1 study · 42 participants
GRADE not reported
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Indomethacin showed no clear difference in oral mucositis (moderate to severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Oral care protocol led to lower oral mucositis (any severity) compared with no treatment/usual care; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Cryotherapy (ice chips) may leads to lower oral mucositis (any severity) compared with no treatment (low certainty).
1 finding from 1 review
Pain after 6 months · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…
Arthroscopy showed no clear difference in pain after 6 months compared with nonsurgical treatment; GRADE not reported.
1 finding from 1 review
Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
Patient preference for active sprays vs placebo nearly attained significance (Chi2 7.259, df=3; P = 0.064); 15/43 participants expressed no desire to continue any spray after the trial.
1 study · 43 participants
GRADE not reported
Pain (VAS/SSI) after 12 months · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…
Arthroscopy led to higher pain (VAS/SSI) after 12 months compared with open surgery; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Prednisone showed no clear difference in oral mucositis (moderate to severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Clinical assessment: nasal alar base augmentation (0 to 3 grading scale) · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)
Artificial bone graft: InFuse (collagen matrix) impregnated with… showed no clear difference in clinical assessment: nasal alar base augmentation (0 to 3 grading… compared with traditional iliac crest cancellous bone graft; GRADE not reported.
1 finding from 1 review
Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
Commercial mouthcare system (Biotene Oral Balance / Xerostom) led to higher xerostomia (VAS mouth dryness) compared with usual care or CMC-based control; GRADE not reported.
1 finding from 1 review
SMD 1.11 [0.33, 1.89]
1 study
GRADE not reported
Pain (VAS) after 12 months · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…
Arthroscopy showed no clear difference in pain (VAS) after 12 months compared with arthrocentesis; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Camomile showed no clear difference in oral mucositis (severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Glutamine showed no clear difference in oral mucositis (severe) compared with placebo/usual care; GRADE not reported.
1 finding from 1 review
RR 0.69 [0.37, 1.29]
5 studies
GRADE not reported
Crepitation (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…
Arthroscopy showed no clear difference in crepitation (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.
1 finding from 1 review
Click (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…
Arthroscopy showed no clear difference in click (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.
1 finding from 1 review