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Evidence found and GRADE certainty

486 questions · 503 findings · 36 reviews · Oral and maxillofacial surgery · related questions CL0289

No studies found 116 · 23.1%GRADE not reported 303 · 60.2%Very low 66 · 13.1%Low 12 · 2.4%Moderate 2 · 0.4%High 4 · 0.8%

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Improvement in nutritional intake · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery

It is very uncertain whether perioperative infraorbital nerve block changes need for analgesic prescription for pain (supplemental analgesic… compared with intravenous analgesia (very low certainty).

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs active control

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Heart rate, respiratory rate, and blood pressure · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Duration of postoperative analgesia · Children up to 13 years of age, undergoing cleft lip repair surgery

It is very uncertain whether perioperative infraorbital nerve block changes duration of postoperative analgesia (in hours) compared with placebo (sham block) (very low certainty).

1 finding from 1 review

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery

It is very uncertain whether perioperative infraorbital nerve block changes pain measured by valid instruments (mean postoperative pain score) compared with placebo (sham block) (very low certainty).

1 finding from 1 review

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block led to higher time to first analgesic requirement compared with infiltration of the incision (peri-incisional infiltration); GRADE not reported.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Improvement of pre-existing accompanying symptoms other than pain · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block may leads to lower need for analgesic prescription for pain (supplemental analgesic… compared with placebo (sham block) (low certainty).

1 finding from 1 review

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

Heart rate, respiratory rate, and blood pressure · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Mortality rate and cause of death · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review

Any intervention for KCOT (e.g. enucleation), alone or combined with an adjunctive therapy (ostectomy, cryotherapy, or Carnoy's solution) vs A different intervention (e.g. enucleation versus marsupialisation), or the same surgical intervention without the adjunctive therapy

Outcome not reported · Adults over the age of 18 with a validated diagnosis of solitary keratocystic odontogenic tumours (KCOT) arising in the jaw bones of the…

The review found no eligible studies for this question.

1 finding from 1 review