Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,916 questions · 3,207 findings · 167 reviews · related questions CL0289

No studies found 596 · 18.6%GRADE not reported 1,666 · 51.9%Very low 603 · 18.8%Low 252 · 7.9%Moderate 78 · 2.4%High 12 · 0.4%

Chinese herbal medicines vs Control (Dobell's solution)

Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies

Chinese herbs (medicine) led to lower oral mucositis (moderate to severe) compared with control (Dobell's solution); GRADE not reported.

1 finding from 1 review

Arthroscopy vs open surgery

Tenderness on palpation in TMJ (clinical evaluation, 12 months) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…

Arthroscopy showed no clear difference in tenderness on palpation in TMJ (clinical evaluation, 12 months) compared with open surgery; GRADE not reported.

1 finding from 1 review

Carboxymethylcellulose (CMC) spray vs Salinum linseed oil spray

Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
  • Andersson 1995 (crossover, n=20): more participants experienced a reduction in oral dryness with linseed (Salinum) spray than with CMC spray; crossover data not accounted for, no usable estimate.
    1 study · 20 participants
    GRADE not reported

Passive maxillary/obturating plate (worn until surgical closure of soft palate) vs No plate

Head circumference (mm) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…

Passive maxillary/obturating plate (worn until surgical closure of… showed no clear difference in head circumference (cm) compared with no plate; GRADE not reported.

1 finding from 1 review

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Radiographic assessment: coronal bone volume (cm3) · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue led to higher radiographic assessment: coronal bone volume (cm3) compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Artificial bone graft: InFuse (collagen matrix) impregnated with rhBMP-2 vs Traditional iliac crest cancellous bone graft

Postoperative complication: persistent oronasal fistula · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)

Artificial bone graft: InFuse (collagen matrix) impregnated with… showed no clear difference in postoperative complication: persistent oronasal fistula compared with traditional iliac crest cancellous bone graft; GRADE not reported.

1 finding from 1 review