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Evidence found and GRADE certainty

211 questions · 317 findings · 16 reviews · Periodontology · related questions CL0289

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No studies found 44 · 13.9%GRADE not reported 184 · 58%Very low 59 · 18.6%Low 21 · 6.6%Moderate 5 · 1.6%High 4 · 1.3%

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Aesthetics · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

The review found no eligible studies for this question.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Attachment change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher change in clinical attachment level (attachment gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

GTR rm associated with bone substitutes vs Open flap debridement (access flap surgery)

Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Radiographic bone change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
1 finding from 1 review
  • Guided tissue regeneration for periodontal infra-bony defects 2006 · Cochrane All outcomes
    >=12 months
    Radiographic data was contained in two studies. Mayfield 1998 showed 0.6 mm gain in bone from the base of the defect in both test and control groups; Ratka-Kruger 2000 reported descriptively that only minute changes in…
    2 studies
    GRADE not reported

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Tooth loss · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
1 finding from 1 review

GTR rm associated with bone substitutes vs Open flap debridement (access flap surgery)

Attachment change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher change in clinical attachment level (attachment gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Change in probing pocket depth (PPD) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher change in probing depth (probing depth reduction) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Disease recurrence (% sites with >=2 mm loss of probing attachment from 12 months after treatment) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

The review found no eligible studies for this question.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Ease of maintenance (% of sites with <4 mm probing depth) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

The review found no eligible studies for this question.

1 finding from 1 review

GTR rm associated with bone substitutes vs Open flap debridement (access flap surgery)

Change in probing pocket depth (PPD) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher change in probing depth (probing depth reduction) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review