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Evidence found and GRADE certainty

397 questions · 449 findings · 37 reviews · Dental caries · related questions CL0289

No studies found 39 · 8.7%GRADE not reported 245 · 54.6%Very low 72 · 16%Low 42 · 9.4%Moderate 51 · 11.4%High 0 · 0%

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) vs Calcium hydroxide + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

OrthoMTA vs RetroMTA

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

OrthoMTA showed no clear difference in clinical failure compared with retroMTA; GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Gutta-percha / AH-Plus

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Extraction of a maxillary first permanent molar vs Extraction of a mandibular first permanent molar

Spontaneous space closure · Children aged 5 to 15 years undergoing first permanent molar extraction

Spontaneous post-extraction space closure did not differ significantly between the maxilla and mandible (pooled OR 2.06, 95% CI 0.46 to 9.28; 3 studies; I2 = 72%); ungraded.

1 finding from 1 review

Bilateral extraction of compromised mandibular first permanent molars vs Age- and gender-matched non-extraction controls

Skeletal development (occlusal plane rotation, facial height) · Children (approximately 11 years or older) with compromised mandibular first permanent molars

Bilateral lower first permanent molar extraction was associated with counter-clockwise rotation of the occlusal plane and a mild decrease in lower anterior face height in one case-control study; ungraded.

1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Zinc oxide and eugenol (ZOE) vs Ozonated sesame oil-zinc oxide (ZO)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

ProRoot MTA vs OrthoMTA

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

ProRoot MTA showed no clear difference in radiological failure compared with orthoMTA; GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Full strength or 1:5 diluted formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) probably leads to lower radiological failure compared with full strength or 1:5 diluted formocresol (FC) (moderate certainty).

1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Non-rinse conditioner + acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review