What do systematic reviews say?

20 questions · 20 findings · 1 reviews · Pain control and patient management · related questions CL0289

Sort:Best matchNewest Highest certainty Download CSV

No studies found 8 · 40%GRADE not reported 0 · 0%Very low 10 · 50%Low 2 · 10%Moderate 0 · 0%High 0 · 0%

4% articaine, 1:100,000 epinephrine vs 2% mepivacaine, 1:100,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% articaine, 1:200,000 epinephrine vs 0.5% bupivacaine, 1:200,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

3% prilocaine, 0.03 IU felypressin vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

2% mepivacaine, 1:20,000 levonordefrin vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 2% mepivacaine, 1:20,000 levonordefrin changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 4.43 [-10.63, 19.48]
2 studies · 458 participants
Very low

4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% prilocaine plain changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -33.95 [-48.05, -19.84]
3 studies · 698 participants
Very low

4% prilocaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% prilocaine, 1:200,000 epinephrine changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -11.80 [-27.76, 4.16]
2 studies · 533 participants
Very low

4% prilocaine, 1:200,000 epinephrine vs 4% prilocaine plain

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% prilocaine, 1:200,000 epinephrine may leads to higher duration of anaesthesia (soft tissue, simulated) compared with 4% prilocaine plain (low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 18.78 [9.02, 28.54]
2 studies · 506 participants
Low

0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 0.5% bupivacaine, 1:200,000 epinephrine changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 222.88 [135.99, 309.76]
6 studies · 232 participants
Very low

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% articaine, 1:100,000 epinephrine may leads to higher duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 56.88 [44.08, 69.69]
2 studies · 422 participants
Low

4% articaine, 1:200,000 epinephrine vs 0.5% bupivacaine, 1:200,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes duration of anaesthesia (soft tissue, simulated) compared with 0.5% bupivacaine, 1:200,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -172.61 [-239.69, -105.53]
2 studies · 39 participants
Very low

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 4% articaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -8.98 [-15.17, -2.79]
5 studies · 162 participants
Very low

4% articaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 10.33 [-22.08, 42.74]
2 studies · 40 participants
Very low

4% articaine plain vs 4% articaine, 1:200,000 epinephrine

It is very uncertain whether 4% articaine plain changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 4% articaine, 1:200,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -28.36 [-42.06, -14.65]
2 studies · 102 participants
Very low

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

It is very uncertain whether 4% articaine, 1:100,000 epinephrine changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 21.87 [-10.96, 54.71]
3 studies · 52 participants
Very low

4% articaine plain vs 4% articaine, 1:100,000 epinephrine

It is very uncertain whether 4% articaine plain changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 4% articaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -37.08 [-60.95, -13.21]
2 studies · 100 participants
Very low