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Evidence found and GRADE certainty

6 questions · 9 findings · 1 reviews · Dental caries · related questions CL0289

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Flavonoids (e.g., quercetin, proanthocyanidin) vs Fluoride agent (e.g., NaF/SDF/KF/CaF2)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Etch-and-Rinse adhesive + biological ACAD protocol network, Flavonoids vs Fluorine showed no significant difference in 24 h bond strength (MD 4.241, 95% CI -2.652 to 11.135; Moderate certainty).

2 findings from 1 review

Flavonoids (e.g., quercetin, proanthocyanidin) vs Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Etch-and-Rinse adhesive + biological ACAD protocol network, Flavonoids showed 12.771 MPa lower 24 h bond strength than Calcium Phosphate (MD -12.771, 95% CI -20.538 to -5.003; Moderate certainty).

2 findings from 1 review

Flavonoids (e.g., quercetin, proanthocyanidin) vs No biomimetic remineralization (control)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Etch-and-Rinse adhesive + biological ACAD protocol network, Flavonoids showed 8.438 MPa higher 24 h bond strength than Control (MD 8.438, 95% CI 2.289 to 14.587; Moderate certainty).

2 findings from 1 review

Flavonoids (e.g., quercetin, proanthocyanidin) vs HEMA/EGDMA-based desensitizer

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Flavonoids vs HEMA showed no significant difference in 24 h bond strength (MD 2.705, 95% CI -5.654 to 11.063; Moderate certainty).

1 finding from 1 review

Flavonoids (e.g., quercetin, proanthocyanidin) vs Calcium-based agent

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Flavonoids vs Calcium showed no significant difference in 24 h bond strength (MD 5.728, 95% CI -2.442 to 13.897; Moderate certainty).

1 finding from 1 review

Flavonoids (e.g., quercetin, proanthocyanidin) vs Mesoporous silica (SiO2)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Flavonoids vs Silica showed no significant difference in 24 h bond strength (MD 3.764, 95% CI -5.241 to 12.769; Moderate certainty).

1 finding from 1 review