Evidence Gaps

What do systematic reviews say?

1 questions · 3 findings · 1 reviews · related questions CL0289

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No studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Autologous platelet concentrates (APC) + open flap debridement (OFD) + bone graft (BG) vs OFD + BG (open flap debridement + bone graft)

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD)… changes change in clinical attachment level (CAL) (mm) compared with OFD + BG (open flap debridement + bone graft) (very low certainty).

3 findings from 1 review

Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
All follow-ups
MD 0.72 [0.43, 1.00]
17 studies · 569 participants
Very low
Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
3 to 6 months
MD 0.47 [0.11, 0.84]
11 studies · 272 participants
GRADE not reported
Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
9 to 12 months · Split-mouth studies only
MD 0.84 [0.62, 1.06]
6 studies · 192 participants
GRADE not reported