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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

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1 questions in 1 reviews · cluster CL0268

current versions

No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

Question	Effect	Evidence	Status / GRADE
Intraoral fluoride-releasing glass bead device attached to the brace vs 250 ppm F (daily) fluoride mouthrinse Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; follow-up 19 months Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane	Additional SoF Table 3. Adverse effects: current design of the fluoride glass bead inadequate; high attrition partly due to bead breakages ('an improved method of attachment is needed'). 37 participants (1 RCT, Luther…	1 study · 37 participants	Very low