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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
20 questions in 3 reviews · cluster CL0246
current versionsNo studies 1 · 5%Ungraded 16 · 80%Very low 0 · 0%Low 0 · 0%Moderate 3 · 15%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Icon resin infiltration vs Baseline before resin infiltration Lightness change · Patients with post-orthodontic white spot lesions and permanent dentition · 6 months Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) | Cohen's d 0.71 [0.32, 1.09] | 1 study | Ungraded |
Icon resin infiltration vs Baseline before resin infiltration Color change · Patients with post-orthodontic white spot lesions and permanent dentition · 6 months Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) | Cohen's d 0.40 [0.11, 0.65] | 1 study | Ungraded |
Icon resin infiltration vs Baseline before resin infiltration Color change · Patients with post-orthodontic white spot lesions and permanent dentition · 6 months Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) | Cohen's d 0.82 [0.43, 1.20] | 1 study | Ungraded |
Icon resin infiltration vs Baseline before resin infiltration Color change · Patients with post-orthodontic white spot lesions and permanent dentition · 6 months Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) | Cohen's d 6.80 [5.70, 7.82] | 1 study | Ungraded |
Icon resin infiltration vs Baseline before resin infiltration Lightness change · Patients with post-orthodontic white spot lesions and permanent dentition · 6 months Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) | Cohen's d -1.76 [-2.22, -1.30] | 1 study | Ungraded |
Icon resin infiltration vs Baseline before resin infiltration Lightness change · Patients with post-orthodontic white spot lesions and permanent dentition · 6 months Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) | Cohen's d 0.40 [0.11, 0.65] | 1 study | Ungraded |
Icon resin infiltration vs Baseline before resin infiltration Color change · Patients with post-orthodontic white spot lesions and permanent dentition · 6 months Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) | Cohen's d 2.37 [1.91, 2.82] | 1 study | Ungraded |
Resin infiltration vs Untreated control (natural remineralization) Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL) · 4 weeks to 6 months Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | SMD 1.24 [0.59, 1.88] | 3 studies · 949 participants | Moderate |
Resin infiltration vs Untreated control (natural remineralization) Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL) · 4 weeks to 6 months, Visual analog scale (Senestraro et al. 2013) Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | SMD 2.34 [1.68, 3.01] | 1 study · 66 participants | Ungraded |
Bleaching before resin infiltration (bleaching + infiltration) vs Resin infiltration alone Patient/dentist satisfaction · Patients with dental fluorosis Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | SMD -1.53 [-4.75, 1.70] | 2 studies | Ungraded |
Resin infiltration vs Fluoride varnish Optical/esthetic improvement (DIAGNOdent reading) · Patients (mainly children) with white spot lesions (WSL) · 3 to 6 months Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | MD 4.76 [0.74, 8.78] | 3 studies · 212 participants | Moderate |
Resin infiltration vs Microabrasion Masking effect / color improvement · Patients with white spot lesions or developmental enamel defects Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | no estimate extracted | 2 studies | Ungraded |
Resin infiltration alone vs In-office bleaching alone Dentist satisfaction (masking effect) · Patients with dental fluorosis Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | MD 3.97 [3.33, 4.61] | 1 study | Ungraded |
Resin infiltration vs Fluoride varnish Optical/esthetic improvement (DIAGNOdent reading) · Patients (mainly children) with white spot lesions (WSL) · 3 to 6 months, Mild lesions, DIAGNOdent score <=14 (Ciftci et al. 2018; Giray et al. 2018) Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | MD 3.65 [0.82, 6.48] | 2 studies · 172 participants | Ungraded |
Resin infiltration vs Fluoride varnish Optical/esthetic improvement (DIAGNOdent reading) · Patients (mainly children) with white spot lesions (WSL) · 3 to 6 months, Severe lesions, DIAGNOdent score >14 (Gozetici et al. 2019) Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | MD 13.15 [3.98, 22.32] | 1 study · 40 participants | Ungraded |
Resin infiltration vs Untreated control (natural remineralization) Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL) · 4 weeks to 6 months, Spectroscopy delta-E (Knosel et al. 2013) Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | SMD 0.63 [0.26, 1.01] | 1 study · 115 participants | Ungraded |
Bleaching before resin infiltration (bleaching + infiltration) vs Resin infiltration alone Masking effect (esthetic improvement) · Patients with dental fluorosis Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | MD -0.30 [-0.98, 0.39] | 2 studies | Moderate |
Resin infiltration vs Untreated control (natural remineralization) Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL) · 4 weeks to 6 months, Modified enamel decalcification index (Cronan 2012) Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or… (2021) | SMD 0.98 [0.83, 1.13] | 1 study · 768 participants | Ungraded |
Micro-invasive treatment (proximal sealing or resin infiltration) vs Conventional invasive treatment (restoration / drill and fill) Outcome NR · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in… Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth (2015) · Cochrane | No studies compared micro-invasive treatments with invasive treatment (fillings) | 0 studies | No studies |
Resin infiltration vs Fluoride varnish, sham/placebo, or flossing advice (non-invasive control) Caries (lesion) progression (radiographic) · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in… · 12 to 36 months (radiographic follow-up), Resin infiltration Micro‐invasive interventions for managing proximal dental decay in primary and permanent teeth (2015) · Cochrane | OR 0.19 [0.08, 0.46] | 2 studies | Ungraded |