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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

6 questions in 3 reviews · cluster CL0162

current versions
No studies 0 · 0%Ungraded 6 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Fluoride varnish combined with fluoride toothpaste vs Fluoride varnish alone
Unacceptability of treatment (drop-outs / leaving study early) · Children or adolescents aged 16 years or less
Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane
RR 0.75 [0.22, 2.59]1 study · 196 participantsUngraded
Fluoride varnish combined with fluoride toothpaste vs Fluoride toothpaste alone
Unacceptability of treatment (drop-outs / leaving study early) · Children or adolescents aged 16 years or less
Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane
RR 1.29 [0.61, 2.71]2 studies · 294 participantsUngraded
Fluoride varnish vs Fluoride toothpaste
Unacceptability of treatment (drop-outs) · Children or adolescents aged 16 or less at the start of the study
One topical fluoride (toothpastes, or mouthrinses, or gels, or varnishes) versus another for preventing… (2004) · Cochrane
RR 1.28 [0.37, 4.41]1 studyUngraded
Fluoride mouthrinse, gel or varnish combined with fluoride toothpaste (any combined regimen) vs Fluoride toothpaste alone
Unacceptability of treatment (drop-outs / leaving study early) · Children or adolescents aged 16 years or less
Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane
RR 1.06 [0.93, 1.22]5 studies · 1998 participantsUngraded
Fluoride varnish vs Fluoride mouthrinse
Unacceptability of treatment (drop-outs) · Children or adolescents aged 16 or less at the start of the study
One topical fluoride (toothpastes, or mouthrinses, or gels, or varnishes) versus another for preventing… (2004) · Cochrane
RR 1.19 [0.86, 1.65]2 studiesUngraded
Topical fluoride therapy (toothpaste, mouthrinse, gel or varnish; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment
Unacceptability of treatment (dropouts/exclusions during the trial) · Children and adolescents aged 16 years or younger · During trial, No-treatment-controlled trials
Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and… (2003) · Cochrane
RR 1.20 [0.85, 1.70]10 studiesUngraded