Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

11 questions in 2 reviews · cluster CL0146

current versions
No studies 1 · 9.1%Ungraded 3 · 27.3%Very low 2 · 18.2%Low 1 · 9.1%Moderate 4 · 36.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs Placebo or no treatment
Decayed, missing and filled primary teeth (dmft) · Pregnant women (for preventing dental caries in the primary teeth of their children)
Fluoride supplementation (with tablets, drops, lozenges or chewing gum) in pregnant women for preventing… (2017) · Cochrane
no estimate extractedNRNo studies
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs No fluoride supplement (placebo or no treatment)
Caries increment on permanent tooth surfaces (D(M)FS) · Children and adolescents (aged 16 years or less at baseline) · 24-36 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.24 [0.16, 0.33]3 studies · 1240 participantsModerate
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs No fluoride supplement (placebo or no treatment)
Caries increment on deciduous tooth surfaces (dmfs) · Children and adolescents (aged 16 years or less at baseline) · 24-36 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.73 [0.46, 0.99]1 study · 115 participantsVery low
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs Topical fluoride (fluoride rinse, varnish or toothpaste)
Caries increment on permanent tooth surfaces (DMFS) · Children and adolescents (aged 16 years or less at baseline) · 96 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.21 [0.04, 0.38]1 studyUngraded
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs No fluoride supplement (placebo or no treatment)
Caries increment on permanent tooth surfaces (DMFS) · Children and adolescents (aged 16 years or less at baseline) · 55 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.25 [0.12, 0.38]1 studyUngraded
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs No fluoride supplement (placebo or no treatment)
Caries increment in permanent teeth (D(M)FT) · Children and adolescents (aged 16 years or less at baseline) · 24-36 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.29 [0.19, 0.39]3 studies · 1208 participantsModerate
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs Other preventive measures (xylitol lozenges)
Caries increment on permanent tooth surfaces (DMFS, approximal surfaces) · Children and adolescents (aged 16 years or less at baseline) · 24-36 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.00 [-0.59, 0.59]1 study · 115 participantsLow
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs Topical fluoride (fluoride rinse, varnish or toothpaste)
Caries increment on permanent tooth surfaces (D(MF)S) · Children and adolescents (aged 16 years or less at baseline) · 24-36 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF -0.10 [-0.25, 0.05]5 studies · 2047 participantsModerate
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs Topical fluoride (fluoride rinse, varnish or toothpaste)
Caries increment on deciduous tooth surfaces (d(m)fs) · Children and adolescents (aged 16 years or less at baseline) · 24-36 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.13 [-0.07, 0.33]2 studies · 1051 participantsModerate
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs No fluoride supplement (placebo or no treatment)
Caries increment on permanent tooth surfaces (DMFS) · Children and adolescents (aged 16 years or less at baseline) · 72 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.28 [0.16, 0.41]1 studyUngraded
Fluoride supplements (tablets, drops, lozenges or chewing gums) vs No fluoride supplement (placebo or no treatment)
Caries increment in deciduous teeth (dmft) · Children and adolescents (aged 16 years or less at baseline) · 24-36 months
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (2011) · Cochrane
PF 0.46 [0.08, 0.83]2 studies · 696 participantsVery low