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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
3 questions in 1 reviews · cluster CL0118
current versionsNo studies 0 · 0%Ungraded 2 · 66.7%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 1 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Drooling Severity and Frequency Scale (DSFS) score · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week), BoNT type A The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | SMD -0.80 [-1.25, -0.36] | 4 studies · 88 participants | Ungraded |
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Drooling Severity and Frequency Scale (DSFS) score · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week), BoNT type B The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | SMD -1.11 [-1.48, -0.74] | 5 studies · 136 participants | Ungraded |
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Drooling Severity and Frequency Scale (DSFS) score · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week) The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | SMD -0.98 [-1.27, -0.70] | 9 studies · 224 participants | High |