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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

55 questions in 7 reviews · cluster CL0108

current versions
No studies 6 · 10.9%Ungraded 39 · 70.9%Very low 7 · 12.7%Low 2 · 3.6%Moderate 1 · 1.8%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Individually designed, patient-centred preventive programme: dietary counselling (snacking timing, regular meals, fermentable carbohydrates) plus toothbrushing counselling, delivered by trained dental hygienists (a multi-intervention) vs Basic prevention offered as standard in public dental clinics
Using xylitol products more than 3 times per day · Children aged 11 to 12 years with at least one active initial caries lesion, screened in a town in Finland · 2 to 4 years
One‐to‐one dietary interventions undertaken in a dental setting to change dietary behaviour (2012) · Cochrane
RR 1.32 [1.04, 1.68]1 study · 497 participantsUngraded
One-to-one advice on sugar restriction: detailed information on the sugar content of foods, with instruction to refrain from sugar-containing foods between meals and to reduce sugar in main meals (6-week sugar restriction) vs No advice on sugar restriction
Total sugar intake frequency (mean number of intakes per day) · Adults with frequent sugar intake harbouring Streptococcus mutans and Streptococcus sobrinus in saliva (14 dental… · Follow-up at 3, 6 and 12 weeks
One‐to‐one dietary interventions undertaken in a dental setting to change dietary behaviour (2012) · Cochrane
Table 5, total mean (SD) intakes/day: intervention 9.5 (1.9) baseline, 1.6 (1.4) at 3 weeks, 1.8 (1.5) at 6 weeks, 7.8 (3.5) at 12 weeks; control 7.2 (2.6), 7.1 (3.7), 6.5 (4.2), 6.7 (2.2). Significant reduction versus…1 study · 20 participantsUngraded
Breastfeeding (post cleft-lip surgery) vs Spoon-feeding
Weight (kg) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or… · 6 weeks post-surgery
Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and… (2011) · Cochrane
MD 0.47 [0.20, 0.74]1 study · 40 participantsUngraded
Maternal advice and support (feeding techniques/breastfeeding positions) vs Usual care (no additional advice/support)
Outcome NR · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or…
Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and… (2011) · Cochrane
No trials were identified that examined the effect of additional maternal support or advice during breastfeeding (or bottle-feeding); no studies evaluated the effectiveness of this intervention (plain-language summary…0 studiesNo studies
Breastfeeding (post cleft-lip surgery) vs Spoon-feeding
Duration of hospital stay (days) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or… · post-surgery
Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and… (2011) · Cochrane
Duration of hospital stay (days): no statistically significant difference between the two groups (Darzi 1996); no pooled estimate displayed (totals not selected).1 study · 40 participantsUngraded