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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
13 questions in 4 reviews · cluster CL0103
current versionsNo studies 1 · 7.7%Ungraded 3 · 23.1%Very low 9 · 69.2%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Package of oral health education/promotion including oral hygiene advice for pregnant women, mothers, infants and young children, plus dietary and feeding practice advice for infants and young children vs Standard care Adverse events for mother or child · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane | One trial (Harrison 2012) reported observing no adverse events; other trials provided no information on adverse events. | 1 study | Ungraded |
Advice about a healthy diet (including breastfeeding promotion and sugar avoidance) and feeding practices (e.g. relating to bottle-feeding and sleep) for infants and young children vs Standard care Adverse events for mother or child · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood… (2024) · Cochrane | One trial only (Feldens 2007) provided information on adverse events and reported no events. | 1 study | Ungraded |
Dietary supplements (Catuama herbal compound) vs Placebo Adverse effects: exacerbation of symptoms · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months), Catuama Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 1.12 [0.33, 3.83] | 1 study · 72 participants | Very low |
Dietary supplements (Catuama herbal compound) vs Placebo Adverse effects: drowsiness · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months), Catuama Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 2.69 [0.11, 63.96] | 1 study · 72 participants | Very low |
Dietary supplements (Catuama herbal compound) vs Placebo Adverse effects: insomnia · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months), Catuama Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 2.69 [0.11, 63.96] | 1 study · 72 participants | Very low |
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs Placebo Adverse effects: intermittent facial skin rash · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months) Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 8.71 [0.37, 205.80] | 1 study · 80 participants | Very low |
Dietary supplements (Catuama herbal compound) vs Placebo Adverse effects: weight gain · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months), Catuama Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 2.69 [0.11, 63.96] | 1 study · 72 participants | Very low |
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs Placebo Adverse effects: gastrointestinal complaints · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months) Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 4.00 [1.21, 13.27] | 3 studies · 138 participants | Very low |
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs Placebo Adverse effects: drowsiness · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months) Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 1.00 [0.07, 14.85] | 1 study · 38 participants | Very low |
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs Placebo Adverse effects: headache · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months) Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 10.87 [1.36, 87.03] | 2 studies · 118 participants | Very low |
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs Placebo Adverse effects: increase in blood pressure · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months) Interventions for treating burning mouth syndrome (2016) · Cochrane | RR 1.00 [0.07, 14.85] | 1 study · 38 participants | Very low |
Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No intervention or delayed intervention (non-intervention control; one trial's control received dental treatment plus an annual supervised toothbrushing session) Adverse events · Children aged 4 to 12 years attending primary school Primary school‐based behavioural interventions for preventing caries (2013) · Cochrane | No study reported any adverse events. | 0 studies | No studies |
Breastfeeding (post cleft-lip surgery) vs Spoon-feeding Adverse events (wound dehiscence; lip scar hypertrophy) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or… · post-surgery Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and… (2011) · Cochrane | Adverse events: one wound dehiscence and one hypertrophy of the lip scar, both in spoon-fed infants (Darzi 1996). | 1 study · 40 participants | Ungraded |