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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

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1 questions in 1 reviews · cluster CL0092

current versions

No studies 0 · 0%Ungraded 1 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

Question	Effect	Evidence	Status / GRADE
Amorphous calcium phosphate (ACP)-containing light-cure adhesive vs Conventional adhesive (Transbond XT) Enamel demineralization (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · 1 and 6 months Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)	Alshammari 2019 (1 triple-blinded RCT, 26 patients / 255 teeth): DIAGNOdent demineralization scores were lower with ACP than control at 1 month (2.58 +/-1.11 vs 3.39 +/-1.29) and 6 months (3.41 +/-1.11 vs 4.32…	1 study · 26 participants	Ungraded