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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
7 questions in 2 reviews · cluster CL0064
current versionsNo studies 0 · 0%Ungraded 2 · 28.6%Very low 4 · 57.1%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate) Incidence of new ICLs (mean number of new lesions per subject) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new… · During fixed orthodontic treatment (development of new lesions), Overall (random-effects model) Distribution of initial caries lesions in relation to fixed orthodontic therapy. A systematic review and… (2024) | MEAN 2.29 [1.12, 3.46] | 5 studies · 208 participants | Very low |
Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate) Incidence of new ICLs (proportion of tooth surfaces developing new lesions) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new… · During fixed orthodontic treatment (development of new lesions), Overall (random-effects model) Distribution of initial caries lesions in relation to fixed orthodontic therapy. A systematic review and… (2024) | Proportion 0.15 [0.08, 0.26] | 4 studies · 1890 participants | Very low |
Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate) Incidence of new ICLs (proportion of subjects developing new lesions) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new… · During fixed orthodontic treatment (development of new lesions), Overall (random-effects model) Distribution of initial caries lesions in relation to fixed orthodontic therapy. A systematic review and… (2024) | Proportion 0.48 [0.33, 0.63] | 7 studies · 533 participants | Very low |
Male sex (boys) vs Female sex (girls) Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of… · At least 24 months follow-up, Gender (boys vs girls) Does Early Childhood Caries Increase Caries Development among School Children and Adolescents? A Systematic… (2022) | OR 0.86 [0.71, 1.02] | 2 studies · 2045 participants | Low |
Caries in first and second primary molars vs Reference (other primary tooth locations / caries-free) Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of… · 8-year follow-up, First and second primary molars Does Early Childhood Caries Increase Caries Development among School Children and Adolescents? A Systematic… (2022) | RR 3.4 [1.8, 6.1] | 1 study · 362 participants | Ungraded |
Caries in upper primary incisors vs Reference (other primary tooth locations / caries-free) Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of… · 8-year follow-up, Upper incisors Does Early Childhood Caries Increase Caries Development among School Children and Adolescents? A Systematic… (2022) | RR 1.6 [1.07, 2.45] | 1 study · 362 participants | Ungraded |
Early childhood caries (caries present in primary dentition) vs No caries in primary dentition (caries-free) Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of… · At least 24 months follow-up (3-12 years) Does Early Childhood Caries Increase Caries Development among School Children and Adolescents? A Systematic… (2022) | OR 3.22 [2.80, 3.71] | 3 studies · 5080 participants | Very low |