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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

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13 questions in 1 reviews · cluster CL0049

current versions

No studies 2 · 15.4%Ungraded 11 · 84.6%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

Question	Effect	Evidence	Status / GRADE
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Kaposi's sarcoma (WHO clinical stage 4) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	Planned WHO stage 4 outcome; no eligible studies (Table 2 lists 'None').	0 studies	No studies
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Mucosal (oral) hyperpigmentation · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 20.35 [3.86, 107.39]	3 studies · 407 participants	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Ulcerative stomatitis · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 28.59 [1.67, 490.32]	1 study · 190 participants	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Dental development / dental age (mineralization chronology) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	Three studies (Fernandes 2007, de Souza 2015, Holderbaum 2005) assessed dental age (Nolla/Willems methods); Fernandes and de Souza found no significant difference between groups; Holderbaum reported mixed sex-specific…	3 studies	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Recurrent oral ulcerations (WHO clinical stage 2) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 6.83 [1.18, 39.53]	3 studies · 284 participants	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Mucocele · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 3.03 [0.12, 75.37]	1 study · 190 participants	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Chronic herpes simplex infection (WHO clinical stage 4) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	Planned WHO stage 4 outcome; no eligible studies (Table 2 lists 'None').	0 studies	No studies
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Poor oral hygiene (simplified oral hygiene index, OHI-S > 3) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 1.23 [0.73, 2.07]	1 study · 837 participants	Ungraded
ART/HAART duration <3 years vs ART/HAART duration >=3 years Oral candidiasis · Children and adolescents living with HIV on ART/HAART · Cross-sectional (case-control; single time point), ART/HAART duration <3 years vs >=3 years Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 17.93 [3.69, 83.12]	2 studies	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Persistent parotid enlargement (WHO clinical stage 2) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 10.36 [0.53, 201.45]	1 study · 60 participants	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Oral hairy leukoplakia (WHO clinical stage 3) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 1.00 [0.06, 16.19]	2 studies · 217 participants	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Angular cheilitis (WHO clinical stage 2) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 1.95 [0.16, 23.65]	2 studies · 224 participants	Ungraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Oral candidiasis (WHO clinical stage 3) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)	OR 16.94 [5.06, 56.70]	5 studies	Ungraded