Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Population

Intervention or exposure

Comparison

Outcome

Any field or review title

Field or topic

Source

Review versions

1 questions in 1 reviews · cluster CL0027

current versions

No studies 0 · 0%Ungraded 1 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

Question	Effect	Evidence	Status / GRADE
E-cigarette use (electronic nicotine delivery systems / vaping) vs Non-smokers (non-users) Oral candidiasis / Candida spp. prevalence · Adult e-cigarette (ENDS) users (general oral health; predominantly natural dentition) An Umbrella Review of E-Cigarettes' Impact on Oral Microbiota and Biofilm Buildup. (2025)	Narrative synthesis: e-cigarette users showed a higher prevalence of Candida spp. (e.g., C. albicans) and increased fungal species compared with non-smokers (Ralho, Camoni [32,28]); no pooled estimate reported.	2 studies	Ungraded