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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

5 questions in 1 reviews · intervention: Systemic/community fluoridation · outcome domain: Caries increment (DMFS/DMFT)

current versions
No studies 1 · 20%Ungraded 1 · 20%Very low 1 · 20%Low 2 · 40%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Initiation of water fluoridation (artificial or natural) vs Low/non-fluoridated water (0.4 ppm fluoride or less)
Caries in permanent teeth (change in DMFT) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years · Follow-up 8 to 11 years
Water fluoridation for the prevention of dental caries (2015) · Cochrane
MD -1.16 [-1.61, -0.72]10 studies · 78764 participantsLow
Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water
Caries in deciduous teeth (dmft/dmfs) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)
Water fluoridation for the prevention of dental caries (2015) · Cochrane
No evidence to determine the effect of the cessation of water fluoridation on caries in deciduous teeth. No included study reported change in dmft following cessation.0 studiesNo studies
Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water
Caries in permanent teeth (DMFS) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience) · Follow-up 3 years
Water fluoridation for the prevention of dental caries (2015) · Cochrane
Insufficient evidence to determine the effect of the cessation of water fluoridation on caries. One study (Maupome 2001), at high risk of bias, over 3 years found no increase in caries in the fluoride-ended group…1 study · 9249 participantsVery low
Initiation of water fluoridation (artificial or natural) vs Low/non-fluoridated water (0.4 ppm fluoride or less)
Caries in deciduous teeth (change in dmft) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years · Follow-up 3 to 12 years
Water fluoridation for the prevention of dental caries (2015) · Cochrane
MD -1.81 [-2.31, -1.31]9 studies · 44268 participantsLow
Initiation of water fluoridation (artificial or natural) vs Low/non-fluoridated water (0.4 ppm fluoride or less)
Caries in permanent teeth (change in DMFS) · Children aged about 12 to 16 years (Hardwick 1982), community setting · Follow-up (single study, Hardwick 1982)
Water fluoridation for the prevention of dental caries (2015) · Cochrane
MD -2.46 [-3.81, -1.11]1 study · 343 participantsUngraded