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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
5 questions in 3 reviews · intervention: Pit-and-fissure sealants · outcome domain: Caries increment (DMFS/DMFT)
current versionsNo studies 0 · 0%Ungraded 5 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Resin-based pit and fissure sealant (PFS) vs Fluoride varnish (FV) DMFS (decayed, missing, filled surfaces) increment, occlusal surfaces · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars · 24 months Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A… (2022) | MD 0.09 [-0.03, 0.21] | 2 studies · 762 participants | Ungraded |
Fluoride-releasing resin-based sealant vs No sealant (no treatment) Mean caries increment (mean number of new cavitated occlusal lesions) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,… · 24 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | Mean number of new cavitated occlusal lesions 0.23 (SD 0.06) in sealed molars vs 0.29 (SD 0.06) in control molars (Wilcoxon matched-pairs signed-rank test P = 0.42) | 1 study · 85 participants | Ungraded |
Glass ionomer-based sealant vs No sealant Mean caries increment (dmft) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric… · 12 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | Joshi 2019: dmft 8.43 (SD 5.84) with sealant vs 10.05 (SD 6.16) with no sealant at 12 months (caries threshold uncertain); Chadwick 2005: no significant difference in caries increment on occlusal surfaces, no summary… | 2 studies | Ungraded |
Resin-based fissure sealant vs Fluoride varnish Change in DMFT (decayed, missing and filled permanent teeth) increment · Children and adolescents from the general population, younger than 20 years of age at the start of the study · 2 years Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of… (2020) · Cochrane | MD -0.08 [-0.14, -0.02] | 1 study · 542 participants | Ungraded |
Resin-based fissure sealant vs Fluoride varnish Change in DMFS (decayed, missing and filled permanent surfaces) increment · Children and adolescents from the general population, younger than 20 years of age at the start of the study · 2 years Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of… (2020) · Cochrane | MD -0.09 [-0.15, -0.03] | 1 study · 542 participants | Ungraded |