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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
5 questions in 3 reviews · intervention: Glass ionomer / ART · outcome domain: White-spot/initial lesions
current versionsNo studies 0 · 0%Ungraded 3 · 60%Very low 2 · 40%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Resin-modified glass-ionomer cement (RM-GIC) for bracket bonding vs Conventional composite resin adhesive (Transbond XT) New white spot lesion incidence (and first-time bracket bond failure) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · During fixed appliance treatment Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024) | Benson 2019 (1 multicenter single-blind RCT, 197 patients): no difference in the proportion of patients with new WSLs or first-time bracket failures between RM-GIC and resin adhesive (p>0.05). No meta-analysis performed. | 1 study · 197 participants | Ungraded |
Fluoride-releasing glass ionomer-based bonding agent vs Non-fluoride glass ionomer-based bonding agent Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 1-24 months follow-up, Glass ionomer-based bonding agent Efficacy of sealants and bonding materials during fixed orthodontic treatment to prevent enamel… (2021) | RR 0.64 [0.41, 0.99] | 1 study · 144 participants | Ungraded |
Glass ionomer cement vs Resin adhesive Incidence of new white spot lesions by visual-tactile assessment · Patients receiving comprehensive fixed orthodontic treatment · 12 to 24 months, Overall Efficacy of sealants and bonding materials during fixed orthodontic treatment to prevent enamel… (2021) | RR 0.72 [0.34, 1.54] | 3 studies · 394 participants | Very low |
Glass ionomer cement (for bracket bonding) vs Resin adhesive (for bracket bonding) Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 12-24 months follow-up Efficacy of sealants and bonding materials during fixed orthodontic treatment to prevent enamel… (2021) | RR 0.72 [0.34, 1.54] | 3 studies · 394 participants | Very low |
Chemically cured glass ionomer cement vs Light-cured compomer (polyacid-modified composite resin) Decalcification (enamel white spot lesions) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or… · Approximately 12 months (to end of treatment) Adhesives for fixed orthodontic bands (2016) · Cochrane | Gillgrass 2001 (98 participants): comparison of change in mean enamel white spot lesion scores during treatment showed no statistically significant difference between chemically cured glass ionomer and light-cured… | 1 study · 98 participants | Ungraded |