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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
5 questions in 2 reviews · intervention: Glass ionomer / ART · outcome domain: Periodontal/gingival
current versionsNo studies 1 · 20%Ungraded 3 · 60%Very low 0 · 0%Low 1 · 20%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Ion-releasing restorations (IRR): RMGIC, HVGIC, GIC, compomer/PMRC, giomer vs Composite resin (CR), including bulk-fill composite Adequate periodontal tissue · Children receiving dental restorations (aged 4-11 years; primary teeth; Class I/II/V cavities) · 1.5 to 2 years Clinical effectiveness of ion-releasing restorations compared to composite restorations in pediatric dental… (2025) | RR 1.13 [0.87, 1.47] | 3 studies · 231 participants | Low |
ART/HAART duration <3 years vs ART/HAART duration >=3 years Other orofacial opportunistic infections (linear gingival erythema, hairy leukoplakia, angular cheilitis, oral ulcers) · Children and adolescents living with HIV on ART/HAART · Cross-sectional (case-control; single time point), ART/HAART duration <3 years vs >=3 years Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) | Except for candidiasis, no significant differences in the prevalence of opportunistic infection manifestations (linear gingival erythema, hairy leukoplakia, angular cheilitis, oral ulcers) between ART duration <3 years… | 2 studies | Ungraded |
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Periodontal disease (gingivitis/periodontitis) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) | OR 3.11 [1.62, 5.97] | 2 studies · 250 participants | Ungraded |
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Acute necrotizing ulcerative gingivitis/periodontitis (WHO clinical stage 3) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) | Planned WHO stage 3 outcome; no eligible studies (Table 2 lists 'None'). | 0 studies | No studies |
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Linear gingival erythema (WHO clinical stage 2) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point) Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) | OR 1.00 [0.06, 16.19] | 2 studies · 224 participants | Ungraded |