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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

12 questions in 2 reviews · intervention: Glass ionomer / ART · outcome domain: Caries increment (DMFS/DMFT)

current versions
No studies 0 · 0%Ungraded 8 · 66.7%Very low 4 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (dmft index, primary dentition) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; dmft index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 0.92 [-0.09, 1.93]5 studies · 1502 participantsVery low
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (dmfs index, primary dentition) · Children and adolescents under 18 years with HIV · Not specified (case-control), Case-control studies; dmfs index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 5.15 [2.20, 8.11]2 studies · 185 participantsUngraded
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (DMFT index, permanent dentition) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; DMFT index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 0.60 [-0.53, 1.72]4 studies · 1390 participantsVery low
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (DMFT index, permanent dentition) · Children and adolescents under 18 years with HIV · Not specified (case-control), Case-control studies; DMFT index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 0.85 [0.04, 1.66]2 studies · 204 participantsVery low
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (dmfs index, primary dentition) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; dmfs index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 4.00 [2.64, 5.36]1 study · 564 participantsUngraded
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (dmft index, primary dentition) · Children and adolescents under 18 years with HIV · Not specified (case-control), Case-control studies; dmft index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 1.53 [1.39, 1.67]2 studies · 185 participantsVery low
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (DMFS index, permanent dentition) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; DMFS index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 2.00 [1.54, 2.46]1 study · 778 participantsUngraded
HIV infection with antiretroviral therapy (ART/HAART) vs HIV-negative individuals
Dental caries severity (DMFS index, permanent dentition) · Children and adolescents under 18 years with HIV · Not specified (case-control), Case-control studies; DMFS index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
MD 1.10 [-0.25, 2.45]1 study · 105 participantsUngraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls
Dental caries prevalence (DMFT/dmft/DMFS/dmfs > 0) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), Permanent dentition (DMFT > 0)
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)
OR 2.49 [1.86, 3.32]1 study · 724 participantsUngraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls
Dental caries prevalence (DMFT/dmft/DMFS/dmfs > 0) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point)
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)
OR 2.70 [2.01, 3.62]2 studies · 1028 participantsUngraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls
Dental caries prevalence (DMFT/dmft/DMFS/dmfs > 0) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), Primary dentition (dmft > 0)
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)
OR 1.93 [1.34, 2.79]1 study · 564 participantsUngraded
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls
Dental caries severity (median DMFT/dmft/DMFS/dmfs) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point)
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022)
Rajonson 2017 reported significantly higher median DMFT/dmft/DMFS/dmfs among CLWH than uninfected children below 12 years; no pooled effect estimate reported.1 studyUngraded