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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
3 questions in 1 reviews · intervention: Exposure: microbial · outcome domain: Adverse effects/fluorosis
current versionsNo studies 0 · 0%Ungraded 2 · 66.7%Very low 0 · 0%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Adverse events (participants with >=1 adverse event) · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week), BoNT type A The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | RD 0.10 [0.00, 0.21] | 5 studies · 117 participants | Ungraded |
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Adverse events (participants with >=1 adverse event) · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week) The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | RD 0.15 [0.05, 0.24] | 10 studies · 249 participants | Low |
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Adverse events (participants with >=1 adverse event) · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week), BoNT type B The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | RD 0.18 [0.04, 0.33] | 5 studies · 132 participants | Ungraded |