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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

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Intervention or exposure

Comparison

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Review versions

1 questions in 1 reviews · intervention: Antimicrobial (other) · outcome domain: White-spot/initial lesions

current versions

No studies 0 · 0%Ungraded 1 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

Question	Effect	Evidence	Status / GRADE
Clearfil Protect Bond antibacterial fluoride-releasing primer vs Transbond XT conventional primer White spot lesion incidence · Patients undergoing fixed orthodontic treatment · Before and after orthodontic treatment Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)	The incidence of WSLs in the Clearfil (CF) group was 8.03%, while in the Transbond (TB) group, it was 9.24% with no significant difference (p = 0.82).	1 study · 35 participants	Ungraded