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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

3 questions in 2 reviews · intervention: Antimicrobial (other) · outcome domain: Periodontal/gingival

current versions
No studies 0 · 0%Ungraded 1 · 33.3%Very low 2 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart
Change in bleeding on probing (BOP) · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive… · 6 to 8 months (SoF); similar at 3 to 4 months
Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults (2022) · Cochrane
MD 2.64 [-8.81, 14.09]3 studies · 80 participantsVery low
Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Full-mouth disinfection (FMD): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours plus adjunctive antiseptic (chlorhexidine) treatments (rinsing, pocket irrigation, tongue/tonsil brushing)
Change in bleeding on probing (BOP) · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive… · 6 to 8 months (SoF); similar at 3 to 4 months
Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults (2022) · Cochrane
MD -0.20 [-13.27, 12.87]2 studies · 42 participantsVery low
Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs No treatment
Bleeding on probing · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
Treating periodontal disease for preventing adverse birth outcomes in pregnant women (2017) · Cochrane
Reported as a secondary periodontal outcome (Analysis 1.9); results not meta-analysed due to considerable heterogeneity (I2 91% to 100%); reduction in favour of periodontal treatment.6 studiesUngraded