Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Gestrinone vs danazol

Side effects ‐ hot flushes · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes side effects: hot flushes compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs leuprolin

Percentage days bleeding or spotting (questionnaire) · women with symptomatic endometriosis

Gestrinone may leads to higher spotting or bleeding compared with leuprolin (low certainty).

1 finding from 1 review

Gestrinone vs danazol

Pelvic pain · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes pelvic pain: none or mild compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs danazol

Dysmenorrhoea: none or mild · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes dysmenorrhoea: none or mild compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs danazol

Dyspareunia: none or mild · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes dyspareunia: none or mild compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs danazol

Side effects ‐ hirsutism · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes side effects: hirsutism compared with danazol (very low certainty).

1 finding from 1 review

Oestrogen in combination with progestogen (sequential or continuous) vs placebo

Withdrawals due to adverse events · women with PMS

It is very uncertain whether oestrogen in combination with progestogen (sequential or continuous) changes withdrawal due to adverse events over 2 to 4 menstrual cycles1 compared with placebo (very low certainty).

1 finding from 1 review

Oestrogen in combination with progestogen (sequential or continuous) vs placebo

Specific adverse events · women with PMS

It is very uncertain whether oestrogen in combination with progestogen (sequential or continuous) changes specific adverse events over 2 to 4 menstrual cycles1 compared with placebo (very low certainty).

1 finding from 1 review