Findings

What do systematic reviews say?

996 questions · 1,049 findings · 79 reviews · Dementia and Cognitive Improvement

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No studies found 240 · 22.9%GRADE not reported 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Dual antiplatelet therapy vs one antiplatelet agent

Any adverse events (excluding major bleeding) · people with cerebral small vessel disease and no dementia

The review found no eligible studies for this question.

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dual antiplatelet therapy vs one antiplatelet agent

Withdrawal from study medication · people with cerebral small vessel disease and no dementia

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 3020 participants
Low

Antiplatelet drug vs placebo

Major bleeding (intracranial and extracranial) · s with mixed prevalence of antiplatelet drug use at baseline, for the prevention of cognitive decline and dementia in people with cerebral…

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 280 participants
Very low

Antiplatelet drug vs placebo

Functional ability · s with mixed prevalence of antiplatelet drug use at baseline, for the prevention of cognitive decline and dementia in people with cerebral…

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 280 participants
Very low

Antiplatelet drug vs placebo

Stroke or transient ischaemic attack · s with mixed prevalence of antiplatelet drug use at baseline, for the prevention of cognitive decline and dementia in people with cerebral…

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 280 participants
Very low

Antiplatelet drug vs placebo

Any adverse events (excluding major bleeding) · s with mixed prevalence of antiplatelet drug use at baseline, for the prevention of cognitive decline and dementia in people with cerebral…

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 280 participants
Very low

Antiplatelet drug vs placebo

Withdrawal from study medication · s with mixed prevalence of antiplatelet drug use at baseline, for the prevention of cognitive decline and dementia in people with cerebral…

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 280 participants
Very low

Antiplatelet therapy vs placebo

Cognitive function · people with cerebral small vessel disease and no dementia

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

Antiplatelet therapy vs placebo

Incidence of dementia · people with cerebral small vessel disease and no dementia

The review found no eligible studies for this question.

1 finding from 1 review

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Organisational interventions vs usual care

Use of physical restraints · older people

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 3 participants
Very low

Summary of findings table ‐ Pressure sensors in bed and chair vs usual care

Adverse events related to the use of physical restraints · older people in general hospital settings

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Pressure sensors in bed and chair vs usual care

Falls · older people in general hospital settings

Summary of findings table ‐ Pressure sensors in bed and chair showed no clear difference in falls compared with usual care (low certainty).

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
RR 1.33 [0.31, 5.79]
1 study · 180 participants
Low

Summary of findings table ‐ Pressure sensors in bed and chair vs usual care

Fall‐related injuries · older people in general hospital settings

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Pressure sensors in bed and chair vs usual care

Mobility · older people in general hospital settings

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 180 participants
Moderate

Summary of findings table ‐ Pressure sensors in bed and chair vs usual care

Challenging behaviour · older people in general hospital settings

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Pressure sensors in bed and chair vs usual care

Quality of life · older people in general hospital settings

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Organisational interventions vs usual care

Adverse events related to the use of physical restraints · older people

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Organisational interventions vs usual care

Number of people who experienced one or more falls · older people

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1743 participants
Very low

Organisational interventions vs usual care

Falls · older people

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low

Organisational interventions vs usual care

Fall‐related injuries · older people

1 finding from 1 review

Interventions for preventing and reducing the use of physical restraints of older people in general hospital settings 2022 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported