Findings

What do systematic reviews say?

2,293 questions · 2,395 findings · 172 reviews · Gut

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No studies found 420 · 17.5%GRADE not reported 60 · 2.5%Very low 821 · 34.3%Low 602 · 25.1%Moderate 397 · 16.6%High 95 · 4%

One‐food elimination diet vs four‐food elimination diet

Clinical improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs four‐food elimination diet

Clinical improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

One‐food elimination diet vs four‐food elimination diet

Histological improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether one‐food elimination diet changes histological improvement at 12 weeks (dichotomous) compared with four‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 2.26 [1.15, 4.43]
1 study · 63 participants
Very low

Corticosteroids vs placebo

Endoscopic improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 596 participants
Low

One‐food elimination diet vs four‐food elimination diet

Histological improvement (continuous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs four‐food elimination diet

Endoscopic improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs four‐food elimination diet

Endoscopic improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

One‐food elimination diet vs four‐food elimination diet

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether one‐food elimination diet changes withdrawals due to adverse events at 12 weeks compared with four‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.33 [0.11, 0.98]
1 study · 63 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Clinical improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs six‐food elimination diet

Clinical improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 129 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Histological improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether one‐food elimination diet changes histological improvement at 6 weeks (dichotomous) compared with six‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.85 [0.54, 1.33]
1 study · 129 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Histological improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 129 participants
Very low

One‐food elimination diet vs six‐food elimination diet

Endoscopic improvement (dichotomous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

One‐food elimination diet vs six‐food elimination diet

Endoscopic improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 129 participants
Very low

Corticosteroids vs placebo

Withdrawals due to adverse events · active EoE patients

Corticosteroids may leads to lower withdrawals due to adverse events (2 to 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.64 [0.43, 0.96]
14 studies · 1032 participants
Low

One‐food elimination diet vs six‐food elimination diet

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether one‐food elimination diet changes withdrawals due to adverse events compared with six‐food elimination diet (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.62 [0.11, 3.57]
1 study · 129 participants
Very low

Four‐food elimination diet with omeprazole vs omeprazole

Clinical improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Four‐food elimination diet with omeprazole vs omeprazole

Clinical improvement (continuous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Four‐food elimination diet with omeprazole vs omeprazole

Histological improvement (dichotomous) · active EoE patients

It is very uncertain whether four‐food elimination diet with omeprazole changes histological improvement at 8 to 12 weeks (dichotomous) compared with omeprazole (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.57 [0.99, 2.48]
1 study · 64 participants
Very low

Four‐food elimination diet with omeprazole vs omeprazole

Histological improvement at 8 to 12 weeks (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low