Findings

What do systematic reviews say?

2,234 questions · 2,325 findings · 216 reviews · Airways

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No studies found 249 · 10.7%GRADE not reported 107 · 4.6%Very low 276 · 11.9%Low 751 · 32.3%Moderate 718 · 30.9%High 224 · 9.6%

Upper limb exercise training vs No upper limb training

Symptoms of dyspnoea · stable COPD

1 finding from 1 review

Upper limb exercise training for COPD 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 129 participants
Moderate

Upper limb exercise training vs No upper limb training

Health‐related quality of life · stable COPD

1 finding from 1 review

Upper limb exercise training for COPD 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 126 participants
Moderate

Upper limb exercise training vs No upper limb training

Peak Upper Limb Exercise Capacity (Supported) · stable COPD

1 finding from 1 review

Upper limb exercise training for COPD 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 70 participants
Low

Upper limb exercise training vs No upper limb training

Peak Upper Limb Exercise Capacity (Unsupported) · stable COPD

1 finding from 1 review

Upper limb exercise training for COPD 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 112 participants
Moderate

Upper limb exercise training vs No upper limb training

Endurance Upper Limb Exercise Capacity (Supported) · stable COPD

1 finding from 1 review

Upper limb exercise training for COPD 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 57 participants
Low

Upper limb exercise training vs No upper limb training

Endurance Upper Limb Exercise Capacity (Unsupported) assessed by total number of rings moved in 6 minutes. · stable COPD

1 finding from 1 review

Upper limb exercise training for COPD 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 142 participants
Low

Upper limb exercise training vs No upper limb training

Upper Limb Strength · stable COPD

1 finding from 1 review

Upper limb exercise training for COPD 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 43 participants
Low

Tailoring asthma treatment using FeNO vs clinical symptoms

Exacerbations · children with asthma

Tailoring asthma treatment using fractional exhaled nitric oxide probably leads to lower number of participants who had ≥ 1 exacerbations over study period… compared with clinical symptoms (moderate certainty).

1 finding from 1 review

Exhaled nitric oxide levels to guide treatment for children with asthma 2016 · Cochrane Headline outcomes only
OR 0.62 [0.49, 0.8]
8 studies · 1279 participants
Moderate

Tailoring asthma treatment using FeNO vs clinical symptoms

Asthma exacerbations · children with asthma

It is very uncertain whether tailoring asthma treatment using fractional exhaled nitric oxide changes number of asthma exacerbations per 52 weeks (exacerbation rate) compared with clinical symptoms (very low certainty).

1 finding from 1 review

Exhaled nitric oxide levels to guide treatment for children with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 736 participants
Very low

Tailoring asthma treatment using FeNO vs clinical symptoms

ICS dose at final visit · children with asthma

1 finding from 1 review

Exhaled nitric oxide levels to guide treatment for children with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 317 participants
Moderate

Tailoring asthma treatment using FeNO vs clinical symptoms

Exacerbations · adults with asthma

Tailoring asthma treatment using FeNO probably leads to lower number of participants who had ≥ 1 exacerbations over study period compared with clinical symptoms (moderate certainty).

1 finding from 1 review

Exhaled nitric oxide levels to guide treatment for adults with asthma 2016 · Cochrane Headline outcomes only
OR 0.6 [0.43, 0.84]
5 studies · 1005 participants
Moderate

Tailoring asthma treatment using FeNO vs clinical symptoms

Annual Exacerbation Rates · adults with asthma

1 finding from 1 review

Exhaled nitric oxide levels to guide treatment for adults with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 842 participants
Moderate

Tailoring asthma treatment using FeNO vs clinical symptoms

ICS dose at final visit · adults with asthma

1 finding from 1 review

Exhaled nitric oxide levels to guide treatment for adults with asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 582 participants
Very low

Intervention not reported

Exacerbations requiring oral corticosteroids 7.3‐month · people with asthma

The intervention showed no clear difference in exacerbations requiring oral corticosteroids 7.3‐month (low certainty).

1 finding from 1 review

Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
OR 0.93 [0.6, 1.44]
4 studies · 466 participants
Low

Intervention not reported

Exacerbations requiring hospital admission 7.8‐month · people with asthma

The intervention showed no clear difference in exacerbations requiring hospital admission 7.8‐month (moderate certainty).

1 finding from 1 review

Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
OR 1.38 [0.51, 3.68]
4 studies · 421 participants
Moderate

Intervention not reported

Asthma control · people with asthma

1 finding from 1 review

Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 4 participants
Very low

Intervention not reported

Serious and non‐serious adverse events · people with asthma

1 finding from 1 review

Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Asthma‐related quality of life (AQLQ)i 9.6‐month · people with asthma

1 finding from 1 review

Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 796 participants
Low

Intervention not reported

Lung function % predicted trough FEV1 higher = better 7.6‐month · people with asthma

1 finding from 1 review

Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 149 participants
Moderate

Intervention not reported

Unscheduled healthcare visits 6.2‐month · people with asthma

It is very uncertain whether the intervention changes unscheduled healthcare visits 6.2‐month (very low certainty).

1 finding from 1 review

Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
OR 0.99 [0.37, 2.62]
3 studies · 430 participants
Very low