Findings

What do systematic reviews say?

1,444 questions · 1,518 findings · 135 reviews · Infectious Diseases

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No studies found 135 · 8.9%GRADE not reported 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%

Fluoroquinolones vs beta‐lactams

Diarrhoea · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes diarrhoea on compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 1.03 [0.45, 2.37]
6 studies · 686 participants
Very low

Fluoroquinolones vs beta‐lactams

Relapse · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes relapse ‐ All trials clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 0.91 [0.11, 7.55]
3 studies · 357 participants
Very low

Fluoroquinolones vs beta‐lactams

Serious adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes serious adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 10.9 [0.61, 194.82]
1 study · 221 participants
Very low

Fluoroquinolones vs beta‐lactams

Discontinuation of medication due to adverse events · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes adverse events leading to discontinuation of treatment compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 1.02 [0.27, 3.89]
1 study · 127 participants
Very low