Withdrawals and adverse effects8 · adults with fibromyalgia
Aquatic training showed no clear difference in withdrawals and adverse effects8 compared with control (low certainty).
1 finding from 1 review
Multidimensional function FIQ Total Score. Scale 0‐100 (lower scores indicate greater health) · adults with fibromyalgia
1 finding from 1 review
Physical function · adults with fibromyalgia
1 finding from 1 review
Health‐related quality of life · anemia in patients with rheumatoid arthritis
1 finding from 1 review
Hemoglobin (Hb) level at the end of the study · anemia in patients with rheumatoid arthritis
1 finding from 1 review
Fatigue ‐ not reported · anemia in patients with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events and drug reactions · anemia in patients with rheumatoid arthritis
1 finding from 1 review
no estimate extracted
1 study · 3 participants
Very low
Withdrawals due to adverse events · anemia in patients with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Lack of efficacy withdrawal · anemia in patients with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawals due to high blood pressure · anemia in patients with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gastrointestinal adverse events · Patients receiving methotrexate for rheumatoid arthritis
Folic or folinic acid (any) probably leads to lower GI side effects (nausea, vomiting, abdominal pain) compared with placebo (moderate certainty).
1 finding from 1 review
Liver toxicity (incidence of transaminase elevation) · Patients receiving methotrexate for rheumatoid arthritis
Folic acid probably leads to lower liver toxicity (ie, incidence of transaminase elevation) compared with placebo (moderate certainty).
1 finding from 1 review
Haematological disorders (neutropenia, etc) · Patients receiving methotrexate for rheumatoid arthritis
Folic acid showed no clear difference in haematological disorders (incidence of neutropenia, etc) compared with placebo (low certainty).
1 finding from 1 review
Acceptability: total withdrawals · Patients receiving methotrexate for rheumatoid arthritis
Folic acid probably leads to lower total withdrawals compared with placebo (moderate certainty).
1 finding from 1 review
Number of swollen joints with folic acid (≤7 mg/wk) Change in number of swollen joints · Patients receiving methotrexate for rheumatoid arthritis
1 finding from 1 review
Number of tender joints with folic acid (≤7 mg/wk) Change in number of tender joints · Patients receiving methotrexate for rheumatoid arthritis
1 finding from 1 review
Gastrointestinal adverse events · Patients receiving methotrexate for rheumatoid arthritis
Folinic acid showed no clear difference in GI side effects (nausea, vomiting, abdominal pain) compared with placebo (moderate certainty).
1 finding from 1 review
Stomatitis / mouth sores (incidence) · Patients receiving methotrexate for rheumatoid arthritis
Folinic acid showed no clear difference in stomatitis / mouth sores (incidence) compared with placebo (moderate certainty).
1 finding from 1 review
Liver toxicity (incidence of transaminase elevation) · Patients receiving methotrexate for rheumatoid arthritis
Folinic acid probably leads to lower liver toxicity (incidence of transaminase elevation) compared with placebo (moderate certainty).
1 finding from 1 review
Haematological disorders (neutropenia, etc) · Patients receiving methotrexate for rheumatoid arthritis
Folinic acid showed no clear difference in haematological disorders (neutropenia, etc) compared with placebo (low certainty).
1 finding from 1 review